Evidence map›Paper›PMID 40582414›Full record

ArticleVirologica Sinica2025

Virome diversity in small mammals from south China: Insights into virus evolution, transmission, and ecology.

Yiwei Shi, Letian Fang, Cixiu Li, Peng Li, Jiluo Liu, Yifan Chen, Yue Zhao, Zishuai Li, Shuqi Liu, Yibo Ding and 10 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Virologica Sinica, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Yiwei ShiDepartment of Epidemiology, Naval Medical University, Shanghai, 200433, China; Key Laboratory of Biological Defense, Ministry of Education, Naval Medical University, Shanghai, 200433, China; Shanghai Key Laboratory of Medical Bioprotection, Naval Medical University, Shanghai, 200433, China.
Letian FangDepartment of Epidemiology, Naval Medical University, Shanghai, 200433, China; Key Laboratory of Biological Defense, Ministry of Education, Naval Medical University, Shanghai, 200433, China; Shanghai Key Laboratory of Medical Bioprotection, Naval Medical University, Shanghai, 200433, China.
Cixiu LiKey Laboratory of Emerging Infectious Diseases in Universities of Shandong, Shandong First Medical University and Shandong Academy of Medical Sciences, Ji'nan, 250117, China; School of Clinical and Basic Medical Sciences, Shandong First Medical University and Shandong Academy of Medical Sciences, Ji'nan, 250117, China; School of Public Health, Shandong First Medical University and Shandong Academy of Medical Sciences, Ji'nan, 250117, China.
Peng LiDepartment of Epidemiology, Naval Medical University, Shanghai, 200433, China; Key Laboratory of Biological Defense, Ministry of Education, Naval Medical University, Shanghai, 200433, China; Shanghai Key Laboratory of Medical Bioprotection, Naval Medical University, Shanghai, 200433, China.
Jiluo LiuDepartment of Epidemiology, Naval Medical University, Shanghai, 200433, China; Key Laboratory of Biological Defense, Ministry of Education, Naval Medical University, Shanghai, 200433, China; Shanghai Key Laboratory of Medical Bioprotection, Naval Medical University, Shanghai, 200433, China.
Yifan ChenDepartment of Epidemiology, Naval Medical University, Shanghai, 200433, China; Key Laboratory of Biological Defense, Ministry of Education, Naval Medical University, Shanghai, 200433, China; Shanghai Key Laboratory of Medical Bioprotection, Naval Medical University, Shanghai, 200433, China.
Yue ZhaoDepartment of Epidemiology, Naval Medical University, Shanghai, 200433, China; Key Laboratory of Biological Defense, Ministry of Education, Naval Medical University, Shanghai, 200433, China; Shanghai Key Laboratory of Medical Bioprotection, Naval Medical University, Shanghai, 200433, China.
Zishuai LiDepartment of Epidemiology, Naval Medical University, Shanghai, 200433, China; Key Laboratory of Biological Defense, Ministry of Education, Naval Medical University, Shanghai, 200433, China; Shanghai Key Laboratory of Medical Bioprotection, Naval Medical University, Shanghai, 200433, China.
Shuqi LiuKey Laboratory of Emerging Infectious Diseases in Universities of Shandong, Shandong First Medical University and Shandong Academy of Medical Sciences, Ji'nan, 250117, China; School of Clinical and Basic Medical Sciences, Shandong First Medical University and Shandong Academy of Medical Sciences, Ji'nan, 250117, China; School of Public Health, Shandong First Medical University and Shandong Academy of Medical Sciences, Ji'nan, 250117, China.
Yibo DingDepartment of Epidemiology, Naval Medical University, Shanghai, 200433, China; Key Laboratory of Biological Defense, Ministry of Education, Naval Medical University, Shanghai, 200433, China; Shanghai Key Laboratory of Medical Bioprotection, Naval Medical University, Shanghai, 200433, China.
Xinyu ZhouDepartment of Epidemiology, Naval Medical University, Shanghai, 200433, China; Key Laboratory of Biological Defense, Ministry of Education, Naval Medical University, Shanghai, 200433, China; Shanghai Key Laboratory of Medical Bioprotection, Naval Medical University, Shanghai, 200433, China.
Dongming JiangDepartment of Epidemiology, Naval Medical University, Shanghai, 200433, China; Key Laboratory of Biological Defense, Ministry of Education, Naval Medical University, Shanghai, 200433, China; Shanghai Key Laboratory of Medical Bioprotection, Naval Medical University, Shanghai, 200433, China.
Jiaying ShenDepartment of Epidemiology, Naval Medical University, Shanghai, 200433, China; Key Laboratory of Biological Defense, Ministry of Education, Naval Medical University, Shanghai, 200433, China; Shanghai Key Laboratory of Medical Bioprotection, Naval Medical University, Shanghai, 200433, China.
Zihan ZhangDepartment of Epidemiology, Naval Medical University, Shanghai, 200433, China; Key Laboratory of Biological Defense, Ministry of Education, Naval Medical University, Shanghai, 200433, China; Shanghai Key Laboratory of Medical Bioprotection, Naval Medical University, Shanghai, 200433, China.
Junheng LyuDepartment of Epidemiology, Naval Medical University, Shanghai, 200433, China; Key Laboratory of Biological Defense, Ministry of Education, Naval Medical University, Shanghai, 200433, China; Shanghai Key Laboratory of Medical Bioprotection, Naval Medical University, Shanghai, 200433, China.
Rui PuDepartment of Epidemiology, Naval Medical University, Shanghai, 200433, China; Key Laboratory of Biological Defense, Ministry of Education, Naval Medical University, Shanghai, 200433, China; Shanghai Key Laboratory of Medical Bioprotection, Naval Medical University, Shanghai, 200433, China.
Xiaojie TanDepartment of Epidemiology, Naval Medical University, Shanghai, 200433, China; Key Laboratory of Biological Defense, Ministry of Education, Naval Medical University, Shanghai, 200433, China; Shanghai Key Laboratory of Medical Bioprotection, Naval Medical University, Shanghai, 200433, China.
Jianhua YinDepartment of Epidemiology, Naval Medical University, Shanghai, 200433, China; Key Laboratory of Biological Defense, Ministry of Education, Naval Medical University, Shanghai, 200433, China; Shanghai Key Laboratory of Medical Bioprotection, Naval Medical University, Shanghai, 200433, China.
Weifeng ShiDepartment of Infectious Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China; Shanghai Institute of Virology, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China. Electronic address: shiwf@ioz.ac.cn.
Guangwen CaoDepartment of Epidemiology, Naval Medical University, Shanghai, 200433, China; Key Laboratory of Biological Defense, Ministry of Education, Naval Medical University, Shanghai, 200433, China; Shanghai Key Laboratory of Medical Bioprotection, Naval Medical University, Shanghai, 200433, China. Electronic address: gcao@smmu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mammals are critical reservoirs of human infectious diseases and the spillover of viruses is related to climate conditions. We conducted meta-transcriptomic sequencing of 226 mammals (bats, rodents, hedgehogs, and shrews) representing 20 species collected across eight cities in south China between 2018 and 2024. Samples included internal organs, oropharyngeal and anal swabs, and feces. We identified 63 vertebrate-associated viruses, including 34 novel viruses. Phylogenetic analysis revealed six viruses with potential infection risks to humans or domestic animals due to their close phylogenetic relationships with known pathogens. Cross-species transmission was observed in 14.3% (9/63) of viruses, shared by at least two host species, with bats, particularly Rhinolophus and Hipposideros, serving as key hubs for viral circulation and zoonotic spillover. Virome composition varied substantially among mammalian species and geographic regions (adonis test, R

Indexed as

MammalsViromeVirus DiseasesVirusesAnimalsChinaChiropteraEvolution, MolecularFecesHedgehogsHumansPhylogenyRodentiaShrewsMeta-transcriptomicsVirus ecologyVirus evolutionWildlife viromeZoonotic disease

Identifiers

PMID40582414
PMCPMC12414398

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.