Evidence map›Paper›PMID 40581912›Full record

ArticleAlimentary pharmacology & therapeutics2025

Research Communication: Prevalence of Acute Reactions After Gluten Ingestion in Patients With Coeliac Disease-A Retrospective Study.

Gabriele Avino, Francesca Burlo, Mauro Perinot, Laura Badina, Grazia Di Leo, Egidio Barbi, Chiara Zanchi

Abstract read
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In one paragraph

Article in Alimentary pharmacology & therapeutics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Gabriele AvinoDepartment of Clinical and Experimental Medicine, Section of Pediatrics, University of Pisa, Pisa, Italy.ORCID https://orcid.org/0009-0003-9703-0942
Francesca BurloDepartment of Medicine, Surgery and Health Science, University of Trieste, Trieste, Italy.
Mauro PerinotDepartment of Medicine, Surgery and Health Science, University of Trieste, Trieste, Italy.
Laura BadinaInstitute for Maternal and Child Health-IRCCS Burlo Garofolo, Trieste, Italy.
Grazia Di LeoInstitute for Maternal and Child Health-IRCCS Burlo Garofolo, Trieste, Italy.
Egidio BarbiDepartment of Medicine, Surgery and Health Science, University of Trieste, Trieste, Italy.
Chiara ZanchiInstitute for Maternal and Child Health-IRCCS Burlo Garofolo, Trieste, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Most gluten exposures in patients with coeliac disease on gluten-free diet were considered asymptomatic or causing chronic symptoms, but some report severe acute reactions like vomiting, diarrhoea and prostration. Assess acute reactions following gluten ingestion. Retrospective study on paediatric and adult patients. A questionnaire investigated symptoms after gluten ingestion. 221 adults and 53 children were enrolled; 72% reported symptoms within 4 h. Vomiting was most common in children, diarrhoea in adults. Patients on gluten-free diet may experience acute symptoms after accidental gluten ingestion. Further research is needed on frequency, triggers, and implications.

Indexed as

Celiac DiseaseDiet, Gluten-FreeGlutensVomitingAcute DiseaseAdolescentAdultAgedChildChild, PreschoolDiarrheaFemaleHumansInfantMaleMiddle AgedGlutenscoeliac diseasedisease‐basedgastroenterologynutritionpaediatrictopics

Identifiers

PMID40581912
PMCPMC12453901

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.