Evidence map›Paper›PMID 40581911›Full record

ArticleEuropean journal of applied physiology2025

Impact of normobaric hyperoxia on finger vasomotor and thermoperceptual responses to local cold in normothermic and mildly hypothermic individuals.

Michail E Keramidas, Heather M Bowes, Maaike I Moes, Ola Eiken, Mikael Gennser

Abstract read
In one paragraph

Article in European journal of applied physiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Michail E KeramidasDivision of Environmental Physiology, Department of Physiology and Pharmacology, Karolinska Institute, Berzelius väg 13, Solna, 171 65, Stockholm, Sweden. michail.keramidas@ki.se.ORCID http://orcid.org/0000-0002-7440-2171
Heather M BowesDivision of Environmental Physiology, Swedish Aerospace Physiology Center, KTH Royal Institute of Technology, Stockholm, Sweden.
Maaike I MoesDivision of Environmental Physiology, Department of Physiology and Pharmacology, Karolinska Institute, Berzelius väg 13, Solna, 171 65, Stockholm, Sweden.
Ola EikenSwedish Air Force, Air Component Command, Joint Medical Division, Uppsala, Sweden.
Mikael GennserDivision of Environmental Physiology, Department of Physiology and Pharmacology, Karolinska Institute, Berzelius väg 13, Solna, 171 65, Stockholm, Sweden.

Funding

Försvarsmakten 9220919
6 · The paper itself

Abstract

aimTo evaluate whether a sustained period of normobaric O

methodsEight healthy men performed a 30-min normoxic and hyperoxic (100% O

resultsDuring the normothermic trial, hyperoxia augmented the cold-induced drop in finger temperature, and attenuated the rewarming (P = 0.03). Hyperoxia also enhanced the sensation of pain (P = 0.04). During the hypothermic trial, hyperoxia did not modify finger temperature, circulatory and perceptual responses to cold (P > 0.05).

conclusionIn normothermia, hyperoxia aggravates finger cold-induced vasoconstriction and pain sensation. In mild hypothermia, however, any hyperoxia-evoked influence on finger vasomotion and thermonociception is overridden by the generalised vasoconstriction and thermal discomfort instigated by whole-body cooling.

Indexed as

FingersHyperoxiaHypothermiaThermosensingVasomotor SystemAdultCold TemperatureHumansMaleOxygenSkin TemperatureVasoconstrictionOxygenCIVDCold injuryDivingImmersionOxygenSkin blood flowThermal pain

Identifiers

PMID40581911
PMCPMC12678452

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.