Trial reportJournal of pediatric gastroenterology and nutrition2025
Children with disorders of gut-brain interaction in primary care versus hospital care: A comparison of characteristics.
Trial report in Journal of pediatric gastroenterology and nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05636358 (Hypnotherapy Through Self-exercises in Children With Functional Abdominal Pain in Primary Care), which is not on this map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Hypnotherapy Through Self-exercises in Children With Functional Abdominal Pain in Primary Care
Who cites it
2 citing papers in PubMed.
- Children with disorders of gut-brain interaction in primary care versus hospital care: A comparison of characteristics.Journal of pediatric gastroenterology and nutrition · 2025Trial
- Psychological Traits and Social Factors Associated with Irritable Bowel Syndrome in Children.Children (Basel, Switzerland) · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
objectivesTo compare characteristics of children with functional abdominal pain (FAP) or irritable bowel syndrome (IBS) between primary and hospital care.
methodsThis study makes a cross-sectional comparison of baseline data from two randomised controlled trials (RCTs): one in Dutch primary care and one in Dutch hospital care, including secondary and tertiary care. This study included children aged 8-17 years old with FAP or IBS fulfilling the Rome III or IV criteria. Outcome measures were age, gender, Rome criteria diagnosis, duration of abdominal pain symptoms, pain intensity and frequency scores, school absenteeism, pain beliefs, somatisation score, anxiety and depression scores, and health-related quality of life scores.
resultsA total of 367 children were compared (110 in primary care, 257 in hospital care). Children seen in primary care were younger (9.8 years, 95% confidence interval [CI]: 9.4-10.7 vs. 13.6 years, 95% CI: 12.9-14.1), had a lower abdominal pain intensity score (12.0, 95% CI: 9.0-13.0 vs. 15.0, 95% CI: 15.0-16.0), frequency score (10.5, 95% CI: 9.0-13.5 vs. 16.0, 95% CI: 14.0-17.0) and somatisation score (15.0, 95% CI: 12.0-17.0 vs. 22.0, 95% CI: 20.0-25.0) compared to hospital care. A lower proportion of children had missed school because of their abdominal pain (57.3%, 95% CI: 48.2-66.4 vs. 75.9%, 95% CI: 70.4-80.9). Other characteristics were similar between groups.
conclusionsChildren in primary care may differ from those in hospital care in terms of age, pain, somatisation, and school absenteeism, suggesting potential treatment response differences. Therefore, research in primary care is needed to guide evidence-based treatment and appropriate referral decisions for general practitioners. CLINICAL
trial registrationPrimary care study: ClinicalTrials.gov NCT05636358. Hospital care study: Dutch Trial Register NL2597.
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