Evidence map›Paper›PMID 40581744›Full record

ReviewJournal of travel medicine2025

Economic value of pre-travel health interventions for communicable diseases in international travellers.

Tijana Stanic, Satoshi Koiso, Naomi F Fields, Allison Taylor Walker, Nora M Mulroy, Edward T Ryan, Regina C LaRocque, Emily P Hyle

Abstract readReview
In one paragraph

Review in Journal of travel medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Tijana StanicMedical Practice Evaluation Center, Massachusetts General Hospital, Boston, MA, USA.
Satoshi KoisoMedical Practice Evaluation Center, Massachusetts General Hospital, Boston, MA, USA.
Naomi F FieldsMedical Practice Evaluation Center, Massachusetts General Hospital, Boston, MA, USA.
Allison Taylor WalkerDivision of Global Migration and Quarantine, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Nora M MulroyMedical Practice Evaluation Center, Massachusetts General Hospital, Boston, MA, USA.
Edward T RyanTraveler's Advice and Immunization Center, Massachusetts General Hospital, Boston, MA, USA.
Regina C LaRocqueTraveler's Advice and Immunization Center, Massachusetts General Hospital, Boston, MA, USA.
Emily P HyleMedical Practice Evaluation Center, Massachusetts General Hospital, Boston, MA, USA.

Funding

CDC HHS U01CK000175CDC HHS U01CK000633Claflin Distinguished Scholars Award (EPH)Intramural CDC HHS CC999999NCEZID CDC HHS U01 CK000175NCEZID CDC HHS U01 CK000633
6 · The paper itself

Abstract

backgroundPre-travel health interventions can reduce the acquisition of communicable diseases and decrease the risk of transmission during or after international travel. We sought to inform policy and research priorities with a scoping literature review of studies that assess the cost-effectiveness of pre-travel interventions.

methodsWe assessed 44 economic evaluation studies published from 1946-2023, regarding pre-travel prevention of hepatitis A, hepatitis B, influenza, malaria, rabies, travellers' diarrhoea, cholera, polio, typhoid fever, measles, and Japanese encephalitis.

resultsPublished studies demonstrate that hepatitis A vaccination, malaria chemoprophylaxis and typhoid vaccination for people travelling to highly endemic settings are likely to be cost-effective, as is measles-mumps-rubella vaccination. The cost-effectiveness of other pre-travel interventions is more sensitive to travel frequency and duration, endemicity at the travel destination, travel purpose (e.g. business, leisure, visiting friends and relatives), risk perceptions (e.g. adherence to care plan, choosing to vaccinate), and costs.

conclusionsCost-effectiveness analyses of pre-travel interventions can inform the value of such interventions, but such analyses depend on the availability of high-quality data regarding clinical outcomes and costs. We propose that international, collaborative networks should collect data and leverage novel technologies to expand the evidence base regarding the risks of exposure, clinical outcomes, risk perception, and costs associated with pre-travel interventions. This evidence base can inform recommendations for specific groups of travellers and the formulation of population-specific health policies.

Indexed as

Communicable Disease ControlCommunicable DiseasesTravelCost-Benefit AnalysisHumansVaccinationcommunicable diseasescost-effectivenessPre-travel health intervention

Identifiers

PMID40581744
PMCPMC12640876

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.