Evidence map›Paper›PMID 40580995›Full record

ArticleThe Lancet. Global health2025

Catastrophic health expenditure, social protection coverage, and financial coping strategies in adults with symptoms of chronic respiratory diseases in Kenya: a cross-sectional study.

Stephen Mulupi, Caroline Waithera, Ewan M Tomeny, Uzochukwu Egere, Helen Meme, Beatrice Kirubi, Jeremiah Chakaya, Edwine Barasa, Miriam Taegtmeyer, Tom Wingfield and 1 more

Abstract read
In one paragraph

Article in The Lancet. Global health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Stephen MulupiInstitute for Resilient Health Systems, Department of International Public Health, Liverpool School of Tropical Medicine, Liverpool, UK; Centre for Respiratory Diseases Research, Kenya Medical Research Institute, Nairobi, Kenya.
Caroline WaitheraCentre for Respiratory Diseases Research, Kenya Medical Research Institute, Nairobi, Kenya.
Ewan M TomenyCentre for Tuberculosis Research, Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK.
Uzochukwu EgereCentre for Tuberculosis Research, Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK.
Helen MemeCentre for Respiratory Diseases Research, Kenya Medical Research Institute, Nairobi, Kenya.
Beatrice KirubiTropical and Infectious Diseases Unit, Liverpool University Hospital NHS Foundation Trust, Liverpool, UK.
Jeremiah ChakayaRespiratory Society of Kenya, Nairobi, Kenya.
Edwine BarasaHealth Economics Research Unit, KEMRI-Wellcome Trust Research Programme, Nairobi, Kenya.
Miriam TaegtmeyerInstitute for Resilient Health Systems, Department of International Public Health, Liverpool School of Tropical Medicine, Liverpool, UK.
Tom WingfieldInstitute for Resilient Health Systems, Department of International Public Health, Liverpool School of Tropical Medicine, Liverpool, UK; Centre for Tuberculosis Research, Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK; Department of Global Public Health, Karolinska Institutet, Stockholm, Sweden; Tropical and Infectious Diseases Unit, Liverpool University Hospital NHS Foundation Trust, Liverpool, UK. Electronic address: tom.wingfield@lstmed.ac.uk.
NIHR International Multidisciplinary Programme to Address Lung Health and TB in Africa Consortium

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDespite the socioeconomic consequences of an increasing burden of chronic respiratory diseases, there is little evidence on the incidence and determinants of catastrophic health expenditure (CHE) in people with chronic respiratory disease symptoms in Kenya. We aimed to generate this evidence by collecting data on medical and non-medical costs, lost income, social protection coverage, and financial coping strategies for such people in Kenya.

methodsWe conducted a cross-sectional survey of consecutively recruited adults seeking care for chronic respiratory disease symptoms at five public health-care facilities in Meru County, Kenya, between Sept 5, 2019, and Oct 1, 2020. Patient costs, National Health Insurance Fund (NHIF) coverage, financial coping strategies, and sociodemographic and clinical data were collected from surveys and medical records. The main study outcomes were the incidence of, and social and health factors associated with, CHE in this cohort. CHE incidence was calculated through the WHO threshold of direct out-of-pocket costs being greater than 10% of a household's monthly total expenditure. Multivariable logistic regression analyses generated adjusted odds ratios (aORs) with 95% CIs of health and social factors associated with CHE, including age, sex, education level, tobacco use, income, being accompanied, poverty level (with the first quintile being the richest to the fifth quintile being the poorest), NHIF usage, coping strategies, final diagnosis, and health system level at which they were seeking care.

findingsOf 319 eligible people invited, 296 (93%) consented to participate and completed surveys. Mean total cost was 1062 Kenyan shillings (KES; 95% CI 896-1228; US$9·1), of which 40·0% was due to direct non-medical costs (KES 425, 95% CI 361-489; $3·7), 36·7% to direct out-of-pocket medical costs (KES 390, 324-456; $3·1), and 23·3% to lost income (KES 247, 153-341, $2·1). 212 (72%) of 296 participants did not have NHIF, 282 (95%) of 296 used coping strategies during care-seeking, and 59 (20%) of 296 were accompanied by a carer during health-care seeking. 76 (26%) of 296 participants had CHE. CHE was associated with being aged 30-44 years old (aOR 2·6, 95% CI 1·3-5·3, p=0·010), being female (1·8, 1·3-2·7, p=0·0021), having higher than secondary school education (1·6, 1·1-2·3, p=0·0083), being accompanied during health-care-seeking visits (3·2, 1·7-5·9, p<0·0001), belonging to the second poverty quintile (2·0, 1·9-2·1, p<0·0001), and seeking care from subcounty hospitals (9·7, 9·6-9·8, p<0·0001) and county hospitals (25·1, 15·7-40·2, p<0·0001).

interpretationThese findings suggest a sizeable burden of CHE in people seeking care for chronic respiratory disease symptoms in Meru County in Kenya, driven by socioeconomic and sex inequalities and impaired access to health care and social protection.

fundingUK-Aid, UK National Institute for Health and Care Research, and UK Research and Innovation.

Indexed as

Adaptation, PsychologicalCatastrophic IllnessHealth ExpendituresRespiratory Tract DiseasesAdolescentAdultChronic DiseaseCoping SkillsCross-Sectional StudiesFemaleHumansKenyaMaleMiddle AgedYoung Adult

Identifiers

PMID40580995
PMCPMC12208783

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.