Evidence map›Paper›PMID 40580446›Full record

ArticleThe British journal of radiology2025

Single-room transcatheter CT hepatic angiography for microwave liver ablation: a feasibility and safety study.

Edward W Johnston, Jodie Basso, Shaira Farooq, Ed McDonagh, Louise Giansante, David Cunningham, Dow-Mu Koh, Martijn Meijerink, Nicos Fotiadis

Abstract read
In one paragraph

Article in The British journal of radiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Edward W JohnstonInterventional Radiology, The Royal Marsden Hospital, London SW36JJ, United Kingdom.ORCID 0000-0002-8504-2968
Jodie BassoInterventional Radiology, The Royal Marsden Hospital, London SW36JJ, United Kingdom.
Shaira FarooqInterventional Radiology, The Royal Marsden Hospital, London SW36JJ, United Kingdom.
Ed McDonaghRadiotherapy and Imaging, Institute of Cancer Research, Sutton SM2 5NG, United Kingdom.
Louise GiansanteJoint Dept. of Physics, The Royal Marsden Hospital, London SW36JJ, United Kingdom.
David CunninghamGastrointestinal Oncology Unit, The Royal Marsden Hospital, London SW36JJ, United Kingdom.
Dow-Mu KohRadiotherapy and Imaging, Institute of Cancer Research, Sutton SM2 5NG, United Kingdom.
Martijn MeijerinkInterventional Radiology, Amsterdam UMC, Amsterdam 1081 HV, Netherlands.
Nicos FotiadisInterventional Radiology, The Royal Marsden Hospital, London SW36JJ, United Kingdom.

Funding

Biomedical Research CentreNational Institute for Health and Care ResearchRoyal Marsden Cancer Charity, and Cancer ResearchRoyal of College of RadiologistsThe Institute of Cancer ResearchThe Royal Marsden NHS Foundation Trust
6 · The paper itself

Abstract

objectivesTranscatheter CT hepatic angiography (CTHA) enhances liver tumour ablation by enabling multiple direct intra-arterial contrast injections during a single procedure. We report the implementation of a single-room CTHA workflow using a mobile fluoroscopic C-arm, focusing on feasibility and safety.

methodsA prospective service evaluation was conducted following a radiation risk assessment and training at an expert centre. Feasibility-defined as the ability to integrate CTHA into a four-hour ablation session-was assessed alongside technical success, which was defined as acquisition of CTHA images. All CTHA-related adverse events were recorded and graded using the Common Terminology Criteria for Adverse Events (CTCAE). Radiation dose, contrast volume, and tumour visualization were also documented.

resultsTwenty patients (14 men, median age 66 years) underwent 21 CTHA procedures (April-September 2024). Feasibility and technical success were 100%, without any instance of CTHA-related complications. Median catheterization time was 10 min16 s, contrast dose was 174 mL (7 acquisitions), and radiation dose-area product was 18.86 Gy·cm2. Ninety-seven percent of tumours (32/33) were visible. All these tumours were completely covered by an ablation zone using image fusion software.

conclusionsSingle-room CTHA using a mobile C-arm is feasible and safe for liver tumour ablation. This technique enhances tumour and ablation zone visibility whilst requiring low contrast volumes, enabling multiple acquisitions and real-time margin assessment. Our technique can be readily implemented without expensive infrastructure, holding significant promise in improving liver ablation outcomes and broadening access to advanced interventional oncology techniques. ADVANCES IN KNOWLEDGE: Single-room CTHA can be readily implemented in centres with catheterization experience, without expensive infrastructure. The method holds significant promise in improving liver ablation outcomes and broadening access to state-of-the-art interventional oncology techniques globally.

Indexed as

Catheter AblationComputed Tomography AngiographyLiver NeoplasmsMicrowavesAgedAged, 80 and overContrast MediaFeasibility StudiesFemaleFluoroscopyHumansLiverMaleMiddle AgedProspective StudiesRadiation DosageContrast Mediaablation techniquescomputed tomography angiographyfluoroscopyliver neoplasmsroboticsrobotic surgical procedurestomographyX-ray computed

Identifiers

PMID40580446
PMCPMC12377462

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.