Evidence map›Paper›PMID 40580382›Full record

Trial reportQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2025

Profiles of quality of life among US young adult cancer survivors and their associations with potential psychosocial intervention targets of hope and psychological flexibility.

Carla J Berg, Laura C Schubel, Darcey M McCready, Sheena Shajan, Palash Bhanot, Campbell Dopke, Afrah Howlader, Pamela S Hinds, Jennifer Levine, Maureen E Lyon and 2 more

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05905250 (An mHealth Positive Psychology Intervention to Reduce Cancer Burden in Young Adult Cancer Survivors), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05905250 nacompletednot on this map

An mHealth Positive Psychology Intervention to Reduce Cancer Burden in Young Adult Cancer Survivors

TypeinterventionalSponsorGeorge Washington UniversityRan2024 to 2025Enrolled155ConditionsSurvivorship, Cancer, Psychological Well-BeingArmsan empirically supported protocol, further refined with evidence-based strategies, Health education
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Carla J BergDepartment of Prevention and Community Health, Milken Institute School of Public Health, George Washington University, Washington, DC, USA. carlaberg@gwu.edu.ORCID http://orcid.org/0000-0001-8931-1961
Laura C SchubelDepartment of Prevention and Community Health, Milken Institute School of Public Health, George Washington University, Washington, DC, USA.
Darcey M McCreadyDepartment of Prevention and Community Health, Milken Institute School of Public Health, George Washington University, Washington, DC, USA.
Sheena ShajanDepartment of Prevention and Community Health, Milken Institute School of Public Health, George Washington University, Washington, DC, USA.
Palash BhanotDepartment of Prevention and Community Health, Milken Institute School of Public Health, George Washington University, Washington, DC, USA.
Campbell DopkeDepartment of Prevention and Community Health, Milken Institute School of Public Health, George Washington University, Washington, DC, USA.
Afrah HowladerDepartment of Health Policy and Management, Milken Institute School of Public Health, George Washington University, Washington, District of Columbia, USA.
Pamela S HindsDivision of Nursing, Department of Nursing Science, Professional Practice & Quality at Children's National and the Department of Pediatrics, School of Medicine and Health Sciences, George Washington University, Washington, District of Columbia, USA.
Jennifer LevineDivision of Nursing, Department of Nursing Science, Professional Practice & Quality at Children's National and the Department of Pediatrics, School of Medicine and Health Sciences, George Washington University, Washington, District of Columbia, USA.
Maureen E LyonDivision of Nursing, Department of Nursing Science, Professional Practice & Quality at Children's National and the Department of Pediatrics, School of Medicine and Health Sciences, George Washington University, Washington, District of Columbia, USA.
Pavani ChalasaniGW Cancer Center, George Washington University, Washington, District of Columbia, USA.
Hannah AremImplementation Science, Healthcare Delivery Research, MedStar Health Research Institute, Washington, District of Columbia, USA.

Funding

An mHealth Positive Psychology Intervention to Reduce Cancer Burden in Young Adult Cancer SurvivorsR21CA261884 · NCI · GEORGE WASHINGTON UNIVERSITY · PI AREM, HANNAH, BERG, CARLA J · 2022 to 2023
$428k
NCI NIH HHS R21CA261884
6 · The paper itself

Abstract

purposeGiven the growing population of young adult (YA) cancer survivors, understanding their different quality of life (QOL) profiles is important for informing interventions to promote QOL, which may target constructs like hope or psychological flexibility. This study assessed YA survivors' QOL profiles and their associations with these 2 constructs.

methodsLatent class analysis (LCA) was conducted on PROMIS QOL measures (physical functioning, social functioning, fatigue, sleep disturbance, pain interference, anxiety, depression) among 155 YA survivors (ages 18-39; M

resultsLCA identified 4 classes: (1) low physical/social functioning with high symptoms (i.e., fatigue, sleep disturbance, pain interference, anxiety, depression; 43.2%); (2) high physical/social functioning with high symptoms (23.9%); (3) high physical/social functioning with low symptoms (17.4%); and (4) low physical functioning, moderate social functioning and physical symptoms, and low mental health symptoms (15.5%). Compared to class 3 (referent), classes 1 and 4 more likely had chemotherapy (aOR = 6.54, CI 1.22-34.48; aOR = 12.82, CI 1.05-28.67), and class 2 had higher monthly income (≥ vs. < $4,200: aOR = 1.16, CI 1.02-1.54). Additionally, classes 1 and 2 had lower hope (B = -10.95, CI -14.42, -7.48; B = -5.50, CI -9.28, -1.71) and higher psychological inflexibility (B = 12.41, CI 9.06, 15.76; B = 8.21, CI 4.57, 11.86).

conclusionsYA survivors demonstrated varied QOL profiles, often with considerable symptoms. Interventions targeting hope and/or psychological flexibility may promote QOL.

trial registrationNCT05905250.

Indexed as

Cancer SurvivorsHopeNeoplasmsPsychosocial InterventionQuality of LifeAdolescentAdultDepressionFatigueFemaleHumansMaleSurveys and QuestionnairesUnited StatesYoung AdultAcceptance and commitment therapyCancer survivorshipHealth promotionHopePositive psychologyQuality of lifeYoung adult cancer survivors

Identifiers

PMID40580382

What OpenQuestion holds

Textmetadata
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.