Evidence map›Paper›PMID 40580098›Full record

ArticleAnnals of medicine2025

Virtual NBI image synthesis using stable diffusion for enhanced recognition of early gastric cancer: a technical validation study.

Changda Lei, Xiuji Kan, Yifan Ouyang, Yutong Mei, Yunbo Guo, Kaicheng Hong, Junbo Li, Bilin Wang, Rui Li

Abstract readValidation Study
In one paragraph

Article in Annals of medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

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3citing papers in PubMed
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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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3 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Changda LeiDepartment of Gastroenterology, The First Affiliated Hospital of Soochow University, Suzhou, China.ORCID 0000-0001-7908-7011
Xiuji KanDepartment of Gastroenterology, The First Affiliated Hospital of Soochow University, Suzhou, China.
Yifan OuyangDepartment of Gastroenterology, The First Affiliated Hospital of Soochow University, Suzhou, China.
Yutong MeiDepartment of Gastroenterology, The First Affiliated Hospital of Soochow University, Suzhou, China.
Yunbo GuoSuzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Science, Suzhou, China.
Kaicheng HongSuzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Science, Suzhou, China.
Junbo LiSuzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Science, Suzhou, China.
Bilin WangSuzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Science, Suzhou, China.
Rui LiDepartment of Gastroenterology, The First Affiliated Hospital of Soochow University, Suzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNarrow band imaging (NBI) can assist endoscopists in detecting early gastric cancer (EGC) more easily, but its widespread use is hindered by economic cost and technical property rights. We aim to realize the conversion of white light endoscopy (WLE) images into virtual narrow band imaging (Vir-NBI) images using stable diffusion.

methodsEndoscopic images were retrospectively collected from 325 patients who underwent endoscopic submucosal dissection (ESD). A total of 273 NBI images from 218 patients were used to fine-tune stable diffusion, which then converted 111 WLE images from 107 patients into Vir-NBI images. Endoscopists assessed the images and evaluated their effectiveness in diagnosing EGC and depicting lesion margins in the form of WLE, NBI, and Vir-NBI image pairs.

resultsCompared with WLE images, Vir-NBI images have better quality. The accuracy of junior endoscopists in diagnosing EGC by observing WLE images alone, simultaneous WLE and NBI images, and simultaneous WLE and Vir-NBI images were 61.26%, 79.28% and 81.08%, respectively. For intermediate endoscopists, the diagnostic accuracy was 72.07%, 86.79% and 84.68%, respectively. For senior endoscopists, the diagnostic accuracy was 80.18%, 95.50% and 92.79%, respectively. In addition,Vir-NBI images had higher area concordance rate andsuccessful whole-lesion diagnosis than WLE images (43.85% vs 39.32%,

conclusionsVir-NBI images has similar observation effect with real NBI image, which helps endoscopists better visualize the lesion structure, thus improving the accuracy of EGC diagnosis.

Indexed as

Early Detection of CancerGastroscopyNarrow Band ImagingStomach NeoplasmsAgedEndoscopic Mucosal ResectionFemaleHumansMaleMiddle AgedRetrospective StudiesArtificial intelligencedeep learningearly gastric cancernarrow band imagingstable diffusion

Identifiers

PMID40580098
PMCPMC12207768

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