Evidence map›Paper›PMID 40579861›Full record

ArticleAmerican journal of human biology : the official journal of the Human Biology Council2025

Sex Ratio at Birth in Northern Ireland During the COVID-19 Pandemic: A Comparison With Published Data From the Republic of Ireland, England and Wales.

Gwinyai Masukume, Peyton Cleaver, Roy K Philip, Victor Grech, Amy L Non

Abstract readComparative Study
In one paragraph

Article in American journal of human biology : the official journal of the Human Biology Council, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Gwinyai MasukumeSchool of Public Health, Physiotherapy and Sports Science, University College Dublin, Dublin, Ireland.ORCID 0000-0002-9251-0264
Peyton CleaverDepartment of Anthropology, University of California San Diego, La Jolla, California, USA.
Roy K PhilipDivision of Neonatology, Department of Paediatrics, University Maternity Hospital Limerick, Limerick, Ireland.ORCID 0000-0002-6097-9869
Victor GrechAcademic Department of Paediatrics, Medical School, Mater Dei Hospital, Msida, Malta.ORCID 0000-0002-3373-0478
Amy L NonDepartment of Anthropology, University of California San Diego, La Jolla, California, USA.ORCID 0000-0001-9781-2985

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe COVID-19 pandemic has been linked in several countries to fluctuations in the proportion of male live births/total live births, known as the sex ratio at birth (SRB). This study investigates how the pandemic influenced SRB patterns in Northern Ireland compared to published data from neighboring regions, including the Republic of Ireland with which it shares an open land border, and England and Wales, across the sea.

methodsMonthly live birth data for Northern Ireland from 2015 to 2021 were obtained from the Northern Ireland Statistics and Research Agency. A time series analysis predicted the SRB for 2020 using data from 2015 to 2019. Predicted and observed SRB values were compared for 2020.

resultsIn August 2020, 5 months after the pandemic declaration, the SRB fell significantly to 49.13%, the period's lowest, below the 95% prediction interval (50.09%-51.85%). In December 2020, 9 months after the declaration, the SRB rose to 54.48%, exceeding the prediction interval (49.75%-51.57%). This overall SRB pattern resembled that in England and Wales but differed from the Republic of Ireland.

conclusionThe decline in SRB in August 2020, occurring 3-5 months after the pandemic declaration, suggests the pandemic disproportionately affected male fetuses in Northern Ireland. The rise in December, 9 months after the declaration, may relate to increased sexual activity in March 2020 following lockdown in a subset of the population. Northern Ireland's SRB pattern aligns more with England and Wales than the Republic of Ireland, indicating that socio-political ties in the United Kingdom may be more influential for pandemic response than geographical proximity.

Indexed as

COVID-19Sex RatioEnglandFemaleHumansInfant, NewbornMaleNorthern IrelandPandemicsSARS-CoV-2WalesCOVID‐19 pandemicmale birthsNorthern Irelandsex ratiostress

Identifiers

PMID40579861
PMCPMC12205282

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.