Evidence map›Paper›PMID 40579779›Full record

ArticleJournal of midwifery & women's health

Postpartum Hemorrhage and the Likelihood of Exclusive Breastfeeding Through 6 Months Postpartum: A Case-Control Study.

Stefanie L Boyles, Sarah R Weinstein, Aleeca F Bell, Elise N Erickson

Abstract read
In one paragraph

Article in Journal of midwifery & women's health. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Stefanie L BoylesUniversity of Arizona, Tucson, Arizona.ORCID 0009-0003-5276-5179
Sarah R WeinsteinUniversity of Arizona, Tucson, Arizona.
Aleeca F BellUniversity of Arizona, Tucson, Arizona.
Elise N EricksonUniversity of Arizona, Tucson, Arizona.ORCID 0000-0002-6655-3500

Funding

Oregon Clinical and Translational Research Institute - The National COVID Cohort Collaborative (N3C)UL1TR002369 · NCATS · OREGON HEALTH & SCIENCE UNIVERSITY · PI Cynthia D Morris, Christopher G. Slatore · 2017 to 2026
$78.4M
Scholars in Women's Health Research Across the LifespanK12HD043488 · NICHD · OREGON HEALTH & SCIENCE UNIVERSITY · PI MYATT, LESLIE · 2002 to 2023
$10.4M
Oxytocin sensitivity and postpartum hemorrhage: testing genetic and epigenetic biomarkers for improving maternal morbidityR01HD111125 · NICHD · UNIVERSITY OF ARIZONA · PI Elise N Erickson · 2023 to 2026
$3.1M
CTRC UL1TR002369NCATS NIH HHS UL1 TR002369NICHD NIH HHS K12 HD043488NICHD NIH HHS R01 HD111125NIH HHS K12HD043488NIH HHS R01HD111125
6 · The paper itself

Abstract

introductionThe purpose of this article is to describe the relationship between postpartum hemorrhage (PPH) and exclusive breastfeeding (EBF) duration among participants who planned to breastfeed their infants. We also describe factors that were protective or prohibitive of breastfeeding.

methodsWe performed a secondary analysis of data from a case-control study examining genetic variations associated with PPH linked to uterine atony in individuals with singleton vaginal births (n = 60case, n = 40 control participants). Bivariate analyses examined the relationships between breastfeeding exclusivity and various factors, including maternal demographics, birth characteristics, and case-control status. Breastfeeding exclusivity, cessation, challenges, and formula introduction were determined from self-reported infant feeding surveys administered to participants at 6 to 10 weeks, 4 months, and 6 months postpartum. Regression models were used to describe the relationship between breastfeeding exclusivity, breastfeeding duration, and PPH, adjusting for relevant confounding variables.

resultsEBF rates for participants with normal postpartum bleeding versus PPH were 82.5% versus 64.1% (P = .05), 77.5% versus 55% (P = .02), and 70.3% versus 49.1% (P = .04) at 6 to 10 weeks, 4 months, and 6 months, respectively. Early EBF (6-10 weeks) was more strongly associated with psychosocial factors, including higher education, lower depression scores, and higher resilience scores. Median ferritin levels at 6 to 10 weeks postpartum were higher in those who continued to exclusively breastfeed at 4 and 6 months (24.1 ng/mL; interquartile range [IQR], 14.7-46.5) compared with those who did not (17.7 ng/mL; IQR, 10.3-32.0) (P = .03 for both). Higher early breastfeeding self-efficacy emerged as the strongest predictor of EBF across all time points. DISCUSSION: PPH significantly impacts breastfeeding initiation and duration, requiring tailored interventions to support affected individuals. Enhancing maternal self-efficacy may improve EBF outcomes. Future research is needed to elucidate the complex relationship between postpartum ferritin levels and EBF outcomes in those who experience PPH.

Indexed as

Breast FeedingPostpartum HemorrhageAdultCase-Control StudiesFemaleHumansInfant, NewbornPostpartum PeriodPregnancyTime FactorsYoung Adultanemiabreastfeedingbreastfeeding durationbreastfeeding exclusivityinfant feedingmaternal morbiditymaternal mortalityobstetric labor complicationsoxytocinpostpartum hemorrhagepregnancy complicationsuterine atony

Identifiers

PMID40579779
PMCPMC12687932

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.