Evidence map›Paper›PMID 40579574›Full record

ArticleSocial psychiatry and psychiatric epidemiology2025

Associations between widowhood status/duration, depression, and cognitive function among community-dwelling Indians age 60 years or older: Exploration of sex and residential factors.

T Muhammad, Christina X Mu, Shobhit Srivastava, Vinod Joseph Kannankeril Joseph, Drishti Drishti, Waad Ali, Preeti Pushpalata Zanwar

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Article in Social psychiatry and psychiatric epidemiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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5 · Who and what money

Authors and funding

7 authors.

T MuhammadDepartment of Human Development and Family Studies| Center for Healthy Aging, Pennsylvania State University, University Park, PA, 16802, USA. muhammad.iips@gmail.com.ORCID http://orcid.org/0000-0003-1486-7038
Christina X MuDepartment of Epidemiology and Biostatistics, University of California, San Francisco, USA.ORCID http://orcid.org/0000-0002-3528-0482
Shobhit SrivastavaInternational Institute for Population Sciences, Mumbai, 400088, Maharashtra, India.
Vinod Joseph Kannankeril JosephAlma Mater Studiorum - Università di Bologna, Via delle Belle Arti, Bologna, BO, Italy.
Drishti DrishtiInternational Institute for Population Sciences, Mumbai, 400088, Maharashtra, India.
Waad AliSultan Qaboos University, Muscat, Oman.
Preeti Pushpalata ZanwarThomas Jefferson University, Philadelphia, PA, USA.

Funding

Translational Epidemiology - Training for Research on Aging and Chronic diseaseT32AG049663 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Elizabeth Rose Mayeda, Mark J Pletcher · 2016 to 2026
$5.8M
NIA NIH HHS T32 AG049663
6 · The paper itself

Abstract

backgroundThe death of a spouse is considered one of the most life challenging stressors. Widowhood has a profound influence on health and may increase the risk of depression and poorer cognitive function. Discriminatory practices in India, such as taboos against remarrying, a lack of occupational opportunities, and social support, may lead to differential widowhood experiences, especially among women. This study examined the associations between widowhood status/duration, depression and cognitive function among community-dwelling men and women in India. Considering the unique cultural and societal context in India, this study also sought to examine differences by sex, rural/urban residence, and multigenerational living status.

methodsWe used baseline data from the Longitudinal Aging Study in India. Data were collected between 2017 and 2019. The study sample consisted of 14,691 men and 15,948 women age ≥ 60 years. Depression was measured using the Short Form Composite International Diagnostic Interview and global cognitive functioning was measured using an assessment adapted from the Mini-Mental State Examination and the cognitive module of the United States Health and Retirement Study, and its sister studies. We employed adjusted multivariable logistic and linear regression models to examine the association of widowhood status/duration with the risk of depression, and cognitive function.

resultsCompared to currently married, those widowed within 0-9 years had a higher risk of depression (Men: aOR = 1.65, 95% CI: 1.20, 2.27; Women: aOR = 1.57, 95% CI = 1.25, 1.98) and worse cognitive functioning (Men: B = 0.80, 95% CI: 0.30, 1.30; Women: B = 0.55, 95% CI = 0.20, 0.91). Among those widowed within 0-9 years, men had a slightly greater risk of worse cognitive functioning than women. As widowhood duration increased, the association between widowhood and worse cognitive functioning was no longer significant among men but remained significant among women. Analyses stratified by rural/urban residence and multigenerational living status and their interactions with widowhood status/duration revealed similar trends. However, the associations between widowhood status/duration and worse cognitive function were more pronounced among women in non-multigenerational households (interaction p <.05).

conclusionsOlder adults who were widowed within 0-9 years had a higher risk of depression and worse cognitive functioning. The adverse effects of widowhood on cognition were no longer significant among men but persisted for women with longer widowhood duration. Non-multigenerational households exacerbated the influence of widowhood on the higher risk of depression and worse cognitive functioning, but findings by urban/rural residence were mixed. Future research should explore what other factors moderate widowhood and health relations and examine changes in widowhood duration over time.

Indexed as

CognitionCognitive DysfunctionDepressionIndependent LivingWidowhoodAgedAged, 80 and overFemaleHumansIndiaLongitudinal StudiesMaleMiddle AgedRisk FactorsRural PopulationSex FactorsCognitive functionDepressive symptomsMultigenerationalRural-urbanWidowhood duration

Identifiers

PMID40579574
PMCPMC12449418

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.