Evidence map›Paper›PMID 40579481›Full record

Trial reportEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2025

Platelet-rich plasma (PRP) therapy to decrease postoperative tonsillectomy pain and bleeding.

Pannipa Wiriyaamornchai, Alena Santeerapharp

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Platelet-rich plasma for post-tonsillectomy pain, haemorrhage, and wound healing: a systematic review and meta-analysis of randomized controlled trials.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Pannipa WiriyaamornchaiDepartment of Otorhinolaryngology-Head & Neck surgery, Faculty of Medicine, HRH Princess Maha Chakri Sirindhorn Medical Center, Srinakharinwirot University, Bangkok, Thailand.ORCID http://orcid.org/0000-0001-7878-5432
Alena SanteerapharpDepartment of Otorhinolaryngology-Head & Neck surgery, Faculty of Medicine, HRH Princess Maha Chakri Sirindhorn Medical Center, Srinakharinwirot University, Bangkok, Thailand. alena@g.swu.ac.th.ORCID http://orcid.org/0000-0001-5592-0849

Funding

Srinakharinwirot University 516/2563
6 · The paper itself

Abstract

purposeThis prospective double-blind randomized controlled trial aimed to assess the benefits of PRP therapy in enhancing wound healing, reducing post-operative bleeding, and alleviating pain in patients undergoing tonsillectomy. By comparing the outcomes of tonsillectomy wounds treated with PRP versus saline.

methodsThe study included 30 patients undergoing tonsillectomy, who were randomly assigned to receive PRP injections on one side and saline injections on the other side at the wound base. Pain levels, wound healing characteristics, and surgical complications such as bleeding were assessed for 28 days post-surgery.

resultsIn this study, there were no cases of post-operative bleeding in the surgical wounds on both sides of all patients. The pain level of the side injected with PRP is statistically significantly lower than the control side from the first day to the 5th day after surgery, there is no statistically significant difference in the pain level between both groups after the 6th day after surgery. The side injected with PRP had significantly faster re-epithelialization on days 7 and 14 post-surgery.

conclusionThis study demonstrates the potential benefits of using PRP in promoting wound healing and reducing pain after tonsillectomy. The findings indicate that PRP injections can be a safe and effective treatment option for patients undergoing tonsillectomy.

Indexed as

Platelet-Rich PlasmaPostoperative HemorrhagePostoperative PainTonsillectomyAdolescentAdultChildDouble-Blind MethodFemaleHumansMalePain MeasurementProspective StudiesTreatment OutcomeWound HealingYoung AdultPost-operative painPRPSurgery of tonsilTonsillar bleedingTonsillectomy

Identifiers

PMID40579481

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.