ArticleScientific reports2025
Synthesis, cytotoxic screening and molecular docking, DFT calculation of novel furan-heterocyclic derivatives as insecticidal agents.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The insecticidal furan-2-carbaldehyde thiosemicarbazone (1) as staring compound underwent a nucleophilic substitution reaction with different reagents, chloroacetyl chloride, chloroacetic acid. 1,4-dibromobutane-2,3-dione and also, with different activated reagents 2-cyanoacetohydrazide, phthalic anhydride, and 2-chloroquinoline-3-carbaldehyde as good yields. The structures of these compounds were confirmed by elemental and spectral analyses. The majority of the synthesized compounds were assessed for their insecticidal activity towards three insects, Cryptoblabes gnidiella, Retithrips syriacus and Spodoptera frugiperda under laboratory conditions and promising results were obtained, with encouraging outcomes observed. Compounds 5, 7, 9, 11 and 15 were found to the most effective than other compounds on all insects. Also, R. syriacus insects are more affected than C. gnidiella and S. frugiperda after one day of treatment with LC
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