ArticleBMJ open respiratory research2025
Breath profiles in paediatric allergic asthma by proton transfer reaction mass spectrometry.
Article in BMJ open respiratory research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Soft ionization by chemical reaction in transfer-high-resolution mass spectrometry for clinical exhaled breath profiling.Analytical and bioanalytical chemistry · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionEnhancing paediatric asthma diagnosis is crucial. Molecular analysis of exhaled breath is a rapidly evolving field aimed at harnessing established and innovative technologies for clinical applications. This study evaluates the feasibility of using online proton-transfer-reaction mass spectrometry (PTR-MS) to identify distinctive breath signatures in children with allergic asthma.
methodsExhaled breath samples of 81 children (41 with allergic asthma and 40 healthy controls) were analysed using the Vocus CI-TOF mass spectrometer (Tofwerk AG, Switzerland), with mass spectra acquired in H
resultsStatistical analysis revealed 89 significant m/z features associated with paediatric allergic asthma, 66 in H
conclusionOur findings demonstrate the suitability of PTR-MS for real-time breath analysis in paediatric populations. Moreover, the identification of distinct breath signatures exclusive to allergic asthma in children suggests the potential of leveraging such technology for non-invasive diagnostic applications.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.