Evidence map›Paper›PMID 40579147›Full record

ArticleNan fang yi ke da xue xue bao = Journal of Southern Medical University2025

[A single repetition time quantitative magnetic susceptibility imaging method for the lumbar spine using bipolar readout gradient].

Zhenxiang Dong, Yihao Guo, Qiang Liu, Yizhe Zhang, Qianyi Qiu, Xiaodong Zhang, Yanqiu Feng

Abstract readEnglish Abstract
PubMed Full text at PMC Publisher
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Article in Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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7 authors.

Zhenxiang DongSchool of Biomedical Engineering, Guangdong Provincial Orthopedic Research Institute, Third Affiliated Hospital of Southern Medical University, Guangzhou 510630, China.
Yihao GuoSchool of Biomedical Engineering, Guangdong Provincial Orthopedic Research Institute, Third Affiliated Hospital of Southern Medical University, Guangzhou 510630, China.
Qiang LiuSchool of Biomedical Engineering, Guangdong Provincial Orthopedic Research Institute, Third Affiliated Hospital of Southern Medical University, Guangzhou 510630, China.
Yizhe ZhangSchool of Biomedical Engineering, Guangdong Provincial Orthopedic Research Institute, Third Affiliated Hospital of Southern Medical University, Guangzhou 510630, China.
Qianyi QiuDepartment of Imaging, Guangdong Provincial Orthopedic Research Institute, Third Affiliated Hospital of Southern Medical University, Guangzhou 510630, China.
Xiaodong ZhangDepartment of Imaging, Guangdong Provincial Orthopedic Research Institute, Third Affiliated Hospital of Southern Medical University, Guangzhou 510630, China.
Yanqiu FengSchool of Biomedical Engineering, Guangdong Provincial Orthopedic Research Institute, Third Affiliated Hospital of Southern Medical University, Guangzhou 510630, China.

Funding

National Natural Science Foundation of China 82372079 and 81871349
6 · The paper itself

Abstract

objectivesTo propose a single repetition time (TR) quantitative magnetic susceptibility imaging method for the lumbar spine using bipolar readout gradient, and compare the quantitative magnetic susceptibility measurement using single TR and dual TR methods for the lumbar spine with different bone densities.

methodsA translation correction method was proposed to correct spatial misalignment along the frequency encoding direction between positive and negative gradient readout images, and the phase difference between the images was eliminated using a phase correction method. The data of lumbar vertebrae L1-L5 were collected using single TR and dual TR methods from 6 normal individuals, 2 patients with osteopenia, and 2 patients with osteoporosis. The magnetic susceptibility map was reconstructed, the quantitative results of single TR before and after correction were compared with those of the dual TR method.

resultsThe linear regression result of the lumbar spine magnetic susceptibility values obtained by the single TR method before calibration and the dual TR method is Y=0.64*X-11.61. The linear regression result of the lumbar spine magnetic susceptibility values corrected by the single TR method and the dual TR method is

conclusionsThe calibrated single TR bipolar readout gradient method can generate artifact-free lumbar spine quantitative magnetic susceptibility distribution maps and reduce data acquisition time by 50%.

Indexed as

Lumbar VertebraeMagnetic Resonance ImagingAdultAgedBone DensityBone Diseases, MetabolicFemaleHumansMaleMiddle AgedOsteoporosislumbar spinemagnetic resonance imagingosteoporosisquantitative susceptibility mappingsingle TR

Identifiers

PMID40579147
PMCPMC12204844

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