Evidence map›Paper›PMID 40579131›Full record

ArticleNan fang yi ke da xue xue bao = Journal of Southern Medical University2025

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Kaiyue Huang, Jingxin Qi, Wenqian Luo, Yixuan Lin, Meimei Chen, Huijuan Gan

Abstract readEnglish Abstract
In one paragraph

Article in Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kaiyue HuangSchool of Traditional Chinese Medicine, Fujian University of Chinese Medicine, Fuzhou 350122, China.
Jingxin QiSchool of Traditional Chinese Medicine, Fujian University of Chinese Medicine, Fuzhou 350122, China.
Wenqian LuoSchool of Traditional Chinese Medicine, Fujian University of Chinese Medicine, Fuzhou 350122, China.
Yixuan LinSchool of Traditional Chinese Medicine, Fujian University of Chinese Medicine, Fuzhou 350122, China.
Meimei ChenSchool of Traditional Chinese Medicine, Fujian University of Chinese Medicine, Fuzhou 350122, China.
Huijuan GanSchool of Traditional Chinese Medicine, Fujian University of Chinese Medicine, Fuzhou 350122, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo investigate the therapeutic mechanism of

methodsForty Wistar rats were randomly divided into normal control group (

resultsThe rat models of phlegm syndrome exhibited severe hepatic steatosis and necrosis, increased body weight, abdominal circumference, Lee's index, FBG, FINS, HOMA-IR, TG, TC, LDL and LPS, and decreased HDL level. The abundance of Bacteroidetes, Megamonas, and Bacteroides in gut microbiota increased while Firmicutes, Lachnospiraceae_NK4A136_group, isohyodeoxycholic acid, and glycohyodeoxycholic acid decreased significantly; hepatic FXR and FGFR4 expressions and ileal FXR and FGF15 expressions decreased while hepatic CYP7A1 expression increased significantly in the rat models. Treatment with

conclusions

Indexed as

Bile Acids and SaltsDrugs, Chinese HerbalGastrointestinal MicrobiomeMetabolic SyndromeAnimalsCholesterol 7-alpha-HydroxylaseFibroblast Growth FactorsLiverMaleRatsRats, WistarReceptor, Farnesoid X-ActivatedReceptors, Cytoplasmic and NuclearBile Acids and SaltsCholesterol 7-alpha-HydroxylaseDrugs, Chinese HerbalFibroblast Growth FactorsReceptor, Farnesoid X-ActivatedReceptors, Cytoplasmic and Nuclearbile acidintestinal florametabolic phenotypemetabolic syndromephlegm syndromeWendan Decoction

Identifiers

PMID40579131
PMCPMC12204833

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.