ArticleJACC. Case reports2025
New Mitral Regurgitation Unveiling Infective Endocarditis in an Adolescent With Mitral Valve Prolapse.
Article in JACC. Case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Management and Imaging Strategies in Pediatric Infective Endocarditis With Mitral Prolapse.JACC. Case reports · 2026Article
- Reply: Management and Imaging Strategies in Pediatric Infective Endocarditis With Mitral Prolapse.JACC. Case reports · 2026Article
- Gerbode defect resulting from ineffective treatment of infective endocarditis: a case report.Cardiovascular ultrasound · 2025Article
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundInfective endocarditis (IE) is a potentially life-threatening condition, possibly occurring in overlap with preexisting structural cardiac abnormalities. The Duke Criteria represent a cornerstone in the diagnosis of IE, and the detection of new regurgitation represents a major criterion that may be overlooked. CASE SUMMARY: We present a case of a 14-year-old girl with mitral valve prolapse (MVP) who developed IE. Despite initial negative echocardiographic findings for vegetations, thorough analysis revealed the presence of a new regurgitation jet at P3 scallop, thereby distinguishing it from the mild preexisting central mitral regurgitation. DISCUSSION: This case highlights the diagnostic challenges of IE when vegetations are absent on echocardiography. In this setting, recognizing a new jet from a preexisting regurgitation is crucial in making the diagnosis. TAKE-HOME MESSAGES: Echocardiography represents the cornerstone for diagnosing IE. Indeed, in patients with MVP, careful assessment of new regurgitation, even in the absence of visible vegetations, should raise suspicion for IE.
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