Evidence map›Paper›PMID 40579077›Full record

ArticleJACC. Case reports2025

Segmental Pulmonary Hypertension in Complex Congenital Heart Disease: The Role of Multimodality Imaging.

Panayotis K Vlachakis, Eva Nyktari, Anastasios Apostolos, Panagiotis Theofilis, Paschalis Karakasis, Andreas Synetos, Konstantinos Toutouzas, Costas Tsioufis, Maria Drakopoulou

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in JACC. Case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. SecondaryJournal of clinical medicine · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Panayotis K VlachakisFirst Cardiology Department, Athens Medical School, Hippokration General Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Eva NyktariCMR Unit, Onassis Cardiac Surgery Center, Kallithea, Greece.
Anastasios ApostolosFirst Cardiology Department, Athens Medical School, Hippokration General Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Panagiotis TheofilisFirst Cardiology Department, Athens Medical School, Hippokration General Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Paschalis KarakasisSecond Department of Cardiology, Hippokration General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Andreas SynetosFirst Cardiology Department, Athens Medical School, Hippokration General Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Konstantinos ToutouzasFirst Cardiology Department, Athens Medical School, Hippokration General Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Costas TsioufisFirst Cardiology Department, Athens Medical School, Hippokration General Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Maria DrakopoulouFirst Cardiology Department, Athens Medical School, Hippokration General Hospital, National and Kapodistrian University of Athens, Athens, Greece. Electronic address: mdrakopoulou@hotmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA 21-year-old male with complex congenital heart disease (pulmonary atresia with intact ventricular septum and major aortopulmonary collateral arteries [MAPCAs]) was seen in our outpatient clinic. Diagnosed shortly after birth, the patient underwent Rashkind atrial septostomy and was deemed amenable to surgical correction/partial unifocalization or palliative intervention. CASE SUMMARY: On examination, the patient was cyanotic with no signs of heart failure. Multimodality imaging showed MAPCAs from the aorta to the pulmonary circulation with a variable degree of stenosis suggestive of segmental pulmonary hypertension (PH). The decision of the multidisciplinary meeting was for a conservative approach and close monitoring with the potential of palliative interventions if there is a deterioration in patients' functional status. DISCUSSION: Segmental PH presents a complex scenario, necessitating multimodality imaging for therapeutic considerations. TAKE-HOME MESSAGE: In cyanotic congenital heart disease, the presence of MAPCAs and segmental PH presents a complex scenario, necessitating multimodality imaging.

Indexed as

congenital heart diseasemultimodality imagingsegmental pulmonary hypertension

Identifiers

PMID40579077
PMCPMC12273813

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.