Evidence map›Paper›PMID 40579015›Full record

ArticleIn vivo (Athens, Greece)

Frequency and Risk Factors of Inappropriate Bladder Filling in Patients Irradiated for High-risk Prostate Cancer.

Dirk Rades, Laura Doehring, Jan-Dirk Küter, Justus Domschikowski, Jon Cacicedo, Stefan Janssen

Abstract read
In one paragraph

Article in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Dirk RadesDepartment of Radiation Oncology, University of Lübeck, Lübeck, Germany; dirk.rades@uksh.de.
Laura DoehringDepartment of Radiation Oncology, University Medical Center Schleswig-Holstein, Lübeck Campus, Lübeck, Germany.
Jan-Dirk KüterDepartment of Radiation Oncology, University Medical Center Schleswig-Holstein, Lübeck Campus, Lübeck, Germany.
Justus DomschikowskiDepartment of Radiotherapy, Malteser Hospital St. Franziskus, Flensburg, Germany.
Jon CacicedoRadiation Oncology Department, University of the Basque Country, Barakaldo, Spain.
Stefan JanssenDepartment of Radiation Oncology, University of Lübeck, Lübeck, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimMany patients with high-risk prostate cancer receive normo-fractionated irradiation. Previously, high-risk cancer and pre-treatment bladder volumes <200 ml were associated with inappropriate bladder filling during the radiotherapy course. A prospective trial will investigate the value of an app reminding patients to drink water before each radiotherapy session. This study provides information regarding magnitude of inappropriate bladder filling and risk factors required for the prospective trial. PATIENTS AND

methodsIn 23 patients with high-risk prostate cancer and inappropriate pre-treatment bladder filling, mean and median numbers of radiation fractions with bladder volumes less than 200 ml and potential risk factors were retrospectively investigated.

resultsMean and median numbers of fractions with volumes less than 200 ml were 29.2±6.6 and 32.0 (interquartile range=24.0-35.0) of 35 fractions. Higher numbers were significantly associated with a lower performance score (

conclusionBladder filling was inappropriate during most radiotherapy fractions and, therefore, must be considered a significant problem. Our results are relevant for a subsequent prospective trial.

Indexed as

Prostatic NeoplasmsUrinary BladderAgedDose Fractionation, RadiationHumansMaleMiddle AgedRetrospective StudiesRisk Factorsbladder fillingHigh-risk prostate cancermagnitudenormo-fractionated irradiationrisk factors

Identifiers

PMID40579015
PMCPMC12223649

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.