Evidence map›Paper›PMID 40579013›Full record

ReviewIn vivo (Athens, Greece)

Giant Cell Tumor of the Proximal Fibula in a 15-year-old Female: A Review and Case Report.

Kazuhiko Hashimoto, Shunji Nishimura, Koji Goto

Abstract readCase ReportsReview
In one paragraph

Review in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Kazuhiko HashimotoDepartment of Orthopedic Surgery, Kindai University Hospital, Ohnohigashi, Japan hazzhiko@med.kindai.ac.jp.
Shunji NishimuraDepartment of Orthopedic Surgery, Kindai University Hospital, Ohnohigashi, Japan.
Koji GotoDepartment of Orthopedic Surgery, Kindai University Hospital, Ohnohigashi, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimGiant cell tumor of the bone (GCTB) is a locally-aggressive, benign tumor that typically affects young adults between 20 and 40 years old. CASE REPORT: A 15-year-old female presented to a primary care physician with pain in the lateral aspect of the left knee and was referred to our department with a suspected bone tumor owing to radiographic findings of osteolysis of the proximal fibula. Computed tomography indicated osteolysis of the proximal fibula, and the bone cortex was thin and partially irregular. Magnetic resonance imaging indicated a mass in the same area, with hyperintense changes in both T1- and T2-weighted images. No biopsy was performed; however, bone tumor curettage and artificial bone grafting were performed. The final pathological examination indicated osteoclastic, multinucleated giant cells. No malignant findings were observed, and the patient was diagnosed with GCTB. No recurrence was observed one year after surgery.

conclusionThis case highlights the occurrence of GCTB in a young patient at an uncommon location. Oncologic surgeons should consider GCTB as a differential diagnosis when an image shows translucency of the proximal fibula, even if the patient is younger than the usual age of onset.

Indexed as

Bone NeoplasmsFibulaGiant Cell Tumor of BoneAdolescentFemaleHumansMagnetic Resonance ImagingTomography, X-Ray Computedcase reportchildFibulagiant cell tumor of bone

Identifiers

PMID40579013
PMCPMC12223642

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.