Evidence map›Paper›PMID 40579001›Full record

ArticleIn vivo (Athens, Greece)

Altered Levels of

Daniel Zavala-Reyes, Juan Manuel Vargas-Morales, Rosa Del Carmen Milán-Segovia, Miguel Ernesto Martínez-Leija, Edith Elena Uresti-Rivera, Oswaldo Hernández-González, Rosana Pelayo-Camacho, Diana Patricia Portales-Pérez

Abstract read
In one paragraph

Article in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Daniel Zavala-ReyesResearch Center for Health Sciences and Biomedicine, Autonomous University of San Luis Potosi, San Luis Potosi, México.
Juan Manuel Vargas-MoralesLaboratory of Immunology and Cellular and Molecular Biology, Faculty of Chemical Sciences, Autonomous University of San Luis Potosi, San Luis Potosi, México.
Rosa Del Carmen Milán-SegoviaLaboratory Bio Pharmacy, Faculty of Chemical Sciences, Autonomous University of San Luis Potosi, San Luis Potosi, México.
Miguel Ernesto Martínez-LeijaResearch Center for Health Sciences and Biomedicine, Autonomous University of San Luis Potosi, San Luis Potosi, México.
Edith Elena Uresti-RiveraResearch Center for Health Sciences and Biomedicine, Autonomous University of San Luis Potosi, San Luis Potosi, México.
Oswaldo Hernández-GonzálezLaboratory of Immunology and Cellular and Molecular Biology, Faculty of Chemical Sciences, Autonomous University of San Luis Potosi, San Luis Potosi, México.
Rosana Pelayo-CamachoEast Biomedical Research Center, Mexican Social Security Institute, Puebla, México.
Diana Patricia Portales-PérezResearch Center for Health Sciences and Biomedicine, Autonomous University of San Luis Potosi, San Luis Potosi, México; dportale@uaslp.mx.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimAcute lymphoblastic leukemia (ALL) is a common childhood cancer characterized by high levels of blasts in the bone marrow, and it is influenced by genetic and microenvironmental factors. Genetic variants of the enzyme arylamine MATERIALS AND

methodsExosomes were isolated from the serum of patients with ALL (n=13) and healthy children (n=18). The size, zeta potential, immunophenotype, and expression of

resultsExosomes from patients with ALL were larger and exhibited lower complexity compared with those from controls, with reduced levels of CD81

conclusionThese findings suggest that exosomes not only reflect the pathophysiology of ALL but may also play a crucial role in its development and progression. Furthermore, exosomes and their non-coding RNA content emerge as potential biomarkers for ALL diagnosis and prognosis, opening avenues for future research to explore their functional role and therapeutic potential.

Indexed as

ExosomesMicroRNAsPrecursor Cell Lymphoblastic Leukemia-LymphomaRNA, Long NoncodingAdolescentBiomarkers, TumorCase-Control StudiesChildChild, PreschoolFemaleHumansImmunophenotypingMaleBiomarkers, TumorH19 long non-coding RNAMicroRNAsRNA, Long NoncodingAcute lymphoblastic leukemiaALLbiomarkerexosomesimmunophenotypelncRNA-H19miR-126miR-1290miR-26bNAT1particle sizezeta potential

Identifiers

PMID40579001
PMCPMC12223628

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.