ArticleIn vivo (Athens, Greece)
The Correlation Between Aortic Stenosis and the Subsequent Incidence of Optic Neuropathy: A Population-based Cohort Study.
Article in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
BACKGROUND/
aimTo survey the potential correlation between aortic stenosis (AS) and subsequent optic neuropathies of glaucoma and ischemic optic neuropathy. PATIENTS AND
methodsA retrospective cohort study was conducted with the use of the TriNetX database, a project by the US Collaborative Network which enrolled 68 healthcare institutions. PSM There were 426,980 and 426,980 people divided into the AS and non-AS groups after exclusion. The primary outcomes were the development of glaucoma and ischemic optic neuropathy. Cox proportional hazard regression was used to produce the adjusted hazard ratio (aHR) and 95% confidence interval (CI) of the optic neuropathies between groups.
resultsThere were 11,717 and 8,676 glaucoma episodes found in the AS and no-AS groups, and there were 566 and 391 ischemic optic neuropathy episodes found in the AS and no-AS groups. The AS group had a significantly higher risk of glaucoma (aHR=1.277, 95% CI=1.242-1.312,
conclusionThe existence of AS correlates to higher risk of developing glaucoma and ischemic optic neuropathy.
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