Evidence map›Paper›PMID 40578973›Full record

ArticleIn vivo (Athens, Greece)

Association of MMP-11 Genotypes With Colorectal Cancer in Taiwan.

Tao-Wei Ke, Ming-Hsien Wu, Ying-Jing Chen, Te-Cheng Yueh, Hou-Yu Shih, Yu-Chen Chang, Yun-Chi Wang, Chia-Wen Tsai, DA-Tian Bau, Wen-Shin Chang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Tao-Wei Ke *Department of Colorectal Surgery, China Medical University Hospital, Taichung, Taiwan, R.O.C.
Ming-Hsien Wu *Graduate Institute of Biomedical Sciences, China Medical University, Taichung, Taiwan, R.O.C.
Ying-Jing Chen *Division of Colorectal Surgery, Department of Surgery, Taichung Veterans General Hospital, Taichung, Taiwan, R.O.C.
Te-Cheng YuehGraduate Institute of Biomedical Sciences, China Medical University, Taichung, Taiwan, R.O.C.
Hou-Yu ShihTerry Fox Cancer Research Laboratory, Department of Medical Research, China Medical University Hospital, Taichung, Taiwan, R.O.C.
Yu-Chen ChangDepartment of Colorectal Surgery, China Medical University Hospital, Taichung, Taiwan, R.O.C.
Yun-Chi WangTerry Fox Cancer Research Laboratory, Department of Medical Research, China Medical University Hospital, Taichung, Taiwan, R.O.C.
Chia-Wen TsaiTerry Fox Cancer Research Laboratory, Department of Medical Research, China Medical University Hospital, Taichung, Taiwan, R.O.C.
DA-Tian Bau *Terry Fox Cancer Research Laboratory, Department of Medical Research, China Medical University Hospital, Taichung, Taiwan, R.O.C.; 013280@tool.caaumed.org.tw.
Wen-Shin Chang *Terry Fox Cancer Research Laboratory, Department of Medical Research, China Medical University Hospital, Taichung, Taiwan, R.O.C.; 031002@tool.caaumed.org.tw.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimMatrix metalloproteinase-11 (MMP-11) is a member of the MMP enzyme family, known for its critical function in extracellular matrix turnover and tissue restructuring. This study aimed to investigate the potential associations between four MATERIALS AND

methodsA total of 362 CRC patients and non-cancer controls were genotyped using the restriction fragment length polymorphism method. The distribution of genotypes and alleles was assessed, and conformity to Hardy-Weinberg equilibrium was confirmed for all examined loci (

resultsNo statistically significant differences were observed in the genotype frequencies of

conclusionAlthough the investigated

Indexed as

Colorectal NeoplasmsGenetic Association StudiesGenetic Predisposition to DiseaseGenotypeMatrix Metalloproteinase 11Polymorphism, Single NucleotideAdultAgedAllelesCase-Control StudiesFemaleGene FrequencyHumansMaleMiddle AgedRisk FactorsMatrix Metalloproteinase 11MMP11 protein, humanColorectal cancergenotypesmatrix metalloproteinase-11single nucleotide polymorphismTaiwan

Identifiers

PMID40578973
PMCPMC12223626

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.