Trial reportJournal of the American Board of Family Medicine : JABFM
Blood Pressure Medication Side Effect Symptoms and Patient Treatment Satisfaction and Adherence.
Trial report in Journal of the American Board of Family Medicine : JABFM. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02996565 (Pragmatic Trial Comparing Telehealth Care and Optimized Clinic-Based Care for Uncontrolled High Blood Pressure), which is not on this map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Pragmatic Trial Comparing Telehealth Care and Optimized Clinic-Based Care for Uncontrolled High Blood Pressure
Who cites it
4 citing papers in PubMed.
- Psychosocial and clinical determinants of medication adherence among elderly chronic disease patients in China.Frontiers in pharmacology · 2026Article
- Synergistic Effects of Compound Dendrobium Candidum and Antihypertensive Medications on Refractory Hypertension in Spontaneously Hypertensive Rats.Cardiology research and practice · 2026Article
- Factors Associated with Treatment Adherence in People with Both Hypertension and Pre-Diabetes: A Cross-Sectional Study in a Semi-Rural Community in Thailand.Patient preference and adherence · 2026Article
- Women's Health Care, Prevention in Practice, and Common Medical Illnesses.Journal of the American Board of Family Medicine : JABFMArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSide effect symptoms to blood pressure (BP) medications may be associated with medication nonadherence, treatment dissatisfaction, and worse BP control. This article describes the frequency and characteristics of BP medication side effect symptoms in a primary care population with poorly controlled hypertension and their relationships to treatment satisfaction and adherence.
methodsPatients in a pragmatic trial were surveyed at baseline to identify and characterize 6 potential BP medication side effect symptoms (tiredness, dizziness, foot swelling, cough, frequent urination, sexual symptoms). Reported symptoms were rated on severity (not a problem, somewhat/moderate problem, big/very big problem) and perceived relatedness to medications (yes/no). Logistic regression models used symptom severity and perceived relatedness to medications to predict BP treatment satisfaction (very satisfied to very dissatisfied) and medication adherence (changing/stopping medications).
resultsAmong survey responders (n = 1,719/3,071, 56%), 90% of respondents taking BP medications reported a symptom that was at least somewhat of a problem. Overall, 39% had at least one symptom that was a big or very big problem and 34% had at least one symptom that they perceived as related to their medication. For most symptoms, both higher problem severity and perceived relatedness to medication were significantly associated with lower BP treatment satisfaction and decreased adherence.
conclusionsBP medication side effect symptoms were very common and often big problems for patients. Identifying and managing them could potentially improve BP outcomes. The brief symptom assessment developed for this study could help identify opportunities to address side effect symptoms and improve patient satisfaction and adherence. CLINICALTRIALS: gov NCT02996565.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.