Evidence map›Paper›PMID 40577335›Full record

ArticlePloS one2025

Optimising access to vocational rehabilitation through multiple sclerosis charities: Protocol for a feasibility randomised controlled trial.

Blanca De Dios Pérez, Denise Kendrick, Roshan das Nair, Nikos Evangelou, Ian Newsome, Kate Radford

Registry-linked trialAbstract readClinical Trial Protocol
In one paragraph

Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06966115 (Optimising Access to Vocational Rehabilitation Through Multiple Sclerosis Charities), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06966115 nanot yet recruitingnot on this map

Optimising Access to Vocational Rehabilitation Through Multiple Sclerosis Charities: A Feasibility Randomised Controlled Trial

TypeinterventionalSponsorUniversity of NottinghamRan2025 to 2027Enrolled60ConditionsMultiple SclerosisArmsMultiple Sclerosis Vocational Rehabilitation (MSVR)
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Blanca De Dios PérezCentre for Rehabilitation and Ageing Research, School of Medicine, University of Nottingham, Nottingham, United Kingdom.ORCID 0000-0002-5621-9445
Denise KendrickCentre for Academic Primary Care, Lifespan and Population Health, School of Medicine, University of Nottingham, Nottingham, United Kingdom.
Roshan das NairMental Health and Clinical Neurosciences, School of Medicine, University of Nottingham, Nottingham, United Kingdom.ORCID 0000-0001-8143-7893
Nikos EvangelouMental Health and Clinical Neurosciences, School of Medicine, University of Nottingham, Nottingham, United Kingdom.
Ian NewsomeLay Co-Author, York, United Kingdom.ORCID 0000-0003-1401-3075
Kate RadfordCentre for Rehabilitation and Ageing Research, School of Medicine, University of Nottingham, Nottingham, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPeople with multiple sclerosis (MS) often leave the workforce prematurely due to MS symptoms and difficulties managing workplace relationships and performance. Vocational rehabilitation (VR) can improve job retention outcomes for people with MS, but there is a lack of evidence on the effectiveness of these interventions.

methodsA multicentre, feasibility, parallel-group randomised controlled trial (RCT) comparing a job retention VR intervention plus usual care (n = 30) with usual care alone (n = 30). This study includes an embedded mixed-methods process evaluation. People with MS, aged 18-65 years, in paid employment will be recruited from MS charities. Participants with MS will be able to include their employers in the intervention to receive information about MS and employment. The intervention involves an initial interview and up to 10 hours of employment support for people with MS and up to four hours of support for employers, over six months. Employees from MS charities will be recruited and trained to deliver the MSVR intervention. Participants will be followed up by postal/telephone/online questionnaires at 6-, 9-, and 12-months post-randomisation. The aim is to ascertain the feasibility and acceptability of delivering the intervention within MS charities, and to determine parameters for future trial and explore the acceptability of the study intervention and procedures. DISCUSSION: This novel study will provide insight into how existing services from MS charities can fill a service gap by providing employment support to people with MS. Findings will inform the design of a future fully powered RCT. TRIAL REGISTRATION NUMBER: ClinicalTrials.gov NCT06966115.

Indexed as

Multiple SclerosisRehabilitation, VocationalAdolescentAdultAgedEmploymentFeasibility StudiesFemaleHumansMaleMiddle AgedRandomized Controlled Trials as TopicYoung Adult

Identifiers

PMID40577335
PMCPMC12204529

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.