Evidence map›Paper›PMID 40577289›Full record

ArticleIEEE computer graphics and applications

The State of Single-Cell Atlas Data Visualization in the Biological Literature.

Mark S Keller, Eric Morth, Thomas C Smits, Simon Warchol, Grace Guo, Qianwen Wang, Robert Krueger, Hanspeter Pfister, Nils Gehlenborg

Abstract read
In one paragraph

Article in IEEE computer graphics and applications. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mark S Keller
Eric Morth
Thomas C Smits
Simon Warchol
Grace Guo
Qianwen Wang
Robert Krueger
Hanspeter Pfister
Nils Gehlenborg

Funding

RESEARCH TRAINING-MEDICAL INFORMATICS 90T15LM007092 · NLM · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI Nils Gehlenborg · 1992 to 2026
$32.8M
Training Program in Bioinformatics and Integrative GenomicsT32HG002295 · NHGRI · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI Peter J Park · 2001 to 2026
$15.8M
Data Exploration and Visualization Tools for HuBMAP and a Human Reference AtlasOT2OD033758 · OD · HARVARD MEDICAL SCHOOL · PI GEHLENBORG, NILS · 2022 to 2024
$5.0M
HuBMAP HIVE Tools Component SupplementOT2OD026677 · OD · HARVARD MEDICAL SCHOOL · PI GEHLENBORG, NILS · 2018 to 2021
$3.5M
Integrative Visualization of Spatiotemporal Tumor AtlasesR33CA263666 · NCI · HARVARD MEDICAL SCHOOL · PI GEHLENBORG, NILS · 2021 to 2021
$1.5M
NCI NIH HHS R33 CA263666NHGRI NIH HHS T32 HG002295NIH HHS OT2 OD026677NIH HHS OT2 OD033758NLM NIH HHS T15 LM007092
6 · The paper itself

Abstract

Recent advancements have enabled tissue samples to be profiled at the unprecedented level of detail of a single cell. Analysis of these data has enabled discoveries that are relevant to understanding disease and developing therapeutics. Large-scale profiling efforts are underway, which aim to generate "atlas" resources that catalog cellular archetypes, including biomarkers and spatial locations. While the problem of cellular data visualization is not new, the size, resolution, and heterogeneity of single-cell atlas datasets present challenges and opportunities. We survey the usage of visualization to interpret single-cell atlas datasets by assessing over 1800 figure panels from 45 biological publications. We intend for this report to serve as a foundational resource for the visualization community as atlas-scale single-cell datasets are emerging rapidly with aims of advancing our understanding of biological function in health and disease.

Indexed as

Atlases as TopicComputer GraphicsData VisualizationSingle-Cell AnalysisDatabases, FactualHumans

Identifiers

PMID40577289
PMCPMC12580505

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.