Evidence map›Paper›PMID 40576936›Full record

ArticleBiological trace element research2026

GPR44-Dependent Regulation of the Selenoproteome by eIF4a3 in Murine Acute Myeloid Leukemia-Initiating Stem Cells.

Deborpita Sarkar, Fenghua Qian, Robert F Paulson, K Sandeep Prabhu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biological trace element research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Deborpita SarkarDepartment of Veterinary and Biomedical Sciences, Center for Molecular Immunology and Infectious Disease and Center for Molecular Toxicology and Carcinogenesis, The Pennsylvania State University, University Park, PA, 16802, USA.
Fenghua QianDepartment of Veterinary and Biomedical Sciences, Center for Molecular Immunology and Infectious Disease and Center for Molecular Toxicology and Carcinogenesis, The Pennsylvania State University, University Park, PA, 16802, USA.
Robert F PaulsonDepartment of Veterinary and Biomedical Sciences, Center for Molecular Immunology and Infectious Disease and Center for Molecular Toxicology and Carcinogenesis, The Pennsylvania State University, University Park, PA, 16802, USA.
K Sandeep PrabhuDepartment of Veterinary and Biomedical Sciences, Center for Molecular Immunology and Infectious Disease and Center for Molecular Toxicology and Carcinogenesis, The Pennsylvania State University, University Park, PA, 16802, USA. ksp4@psu.edu.

Funding

Research Training in Physiological Adaptations to StressT32GM108563 · NIGMS · PENNSYLVANIA STATE UNIVERSITY, THE · PI CANTORNA, MARGHERITA T, KORZICK, DONNA HOPE · 2014 to 2023
$2.2M
Research Training in Physiological Adaptations to StressT32GM154124 · NIGMS · PENNSYLVANIA STATE UNIVERSITY, THE · PI MARGHERITA T CANTORNA, Kevin John Harvatine · 2024 to 2026
$1.5M
National Institute of Food and Agriculture PEN04932; Accession 7006585NIGMS NIH HHS T32 GM108563NIGMS NIH HHS T32 GM154124NIH HHS T32GM154124/T32GM108563
6 · The paper itself

Abstract

Acute myeloid leukemia (AML) remains an aggressive hematologic malignancy, with leukemia-initiating stem cells (LICs) playing a critical role in disease progression and therapeutic resistance. In this study, we investigated the role of GPR44, a G-protein coupled receptor of arachidonic acid-derived prostaglandin D

Indexed as

Leukemia, Myeloid, AcuteNeoplastic Stem CellsProteomeReceptors, G-Protein-CoupledSelenoproteinsAnimalsMiceMice, Inbred C57BLMice, KnockoutProteomeReceptors, G-Protein-CoupledSelenoproteinsCyclopentenone prostaglandinsGPCRMRNA stabilityPTGDR2SeleniumSelenoprotein hierarchy

Identifiers

PMID40576936
PMCPMC12847157

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.