Evidence map›Paper›PMID 40576844›Full record

ArticleArchives of virology2025

Appearance and spread of norovirus genotype GII.17 subcluster C2 (Romania-2021 like) in Nizhny Novgorod, Russia, 2021-2023.

Natalia V Epifanova, S V Oparina, O V Morozova, T A Sashina, A E Alekseeva, N A Novikova

Abstract read
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Article in Archives of virology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Natalia V EpifanovaLaboratory of Molecular Epidemiology of Viral Infections, I.N. Blokhina Nizhny Novgorod Research Institute of Epidemiology and Microbiology, Nizhny Novgorod, Russian Federation. epifanovanv@mail.ru.ORCID https://orcid.org/0000-0001-7679-8029
S V OparinaLaboratory of Molecular Epidemiology of Viral Infections, I.N. Blokhina Nizhny Novgorod Research Institute of Epidemiology and Microbiology, Nizhny Novgorod, Russian Federation.ORCID https://orcid.org/0000-0003-1161-1344
O V MorozovaLaboratory of Molecular Epidemiology of Viral Infections, I.N. Blokhina Nizhny Novgorod Research Institute of Epidemiology and Microbiology, Nizhny Novgorod, Russian Federation.ORCID https://orcid.org/0000-0002-8058-8187
T A SashinaLaboratory of Molecular Epidemiology of Viral Infections, I.N. Blokhina Nizhny Novgorod Research Institute of Epidemiology and Microbiology, Nizhny Novgorod, Russian Federation.ORCID https://orcid.org/0000-0003-3203-7863
A E AlekseevaLaboratory of Molecular Epidemiology of Viral Infections, I.N. Blokhina Nizhny Novgorod Research Institute of Epidemiology and Microbiology, Nizhny Novgorod, Russian Federation.ORCID https://orcid.org/0000-0001-6482-0268
N A NovikovaLaboratory of Molecular Epidemiology of Viral Infections, I.N. Blokhina Nizhny Novgorod Research Institute of Epidemiology and Microbiology, Nizhny Novgorod, Russian Federation.ORCID https://orcid.org/0000-0002-3710-6648

Funding

Russian Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing Russian Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing
6 · The paper itself

Abstract

Noroviruses are one of the leading causes of acute gastroenteritis worldwide and have significant genetic diversity. In this study, based on phylogenetic analysis of genome sequences of noroviruses circulating in Nizhny Novgorod in 2014–2023 and previously published sequences obtained from the GenBank database, we show a return to active circulation of cluster C of genotype GII.17[P17], which was displaced in 2015–2016 by cluster D. A new subcluster, C2 (Romania-2021 like), was identified and found to be different from subcluster C1 (Kawasaki-2014), which circulated in the middle of the last decade. Amino acid substitutions characteristic of C2 were found in the main structural protein VP1, bringing it closer to the Tokyo_JP_1976 strain identified in the 1970s. It was established that representatives of the C2 subcluster (Romania-2021 like) circulated in 2021–2023 in European and American countries and caused outbreaks of norovirus infection. The data obtained indicate that the evolution of the phylogenetic lineage represented by cluster C of the GII.17 genotype continued in the last decade and had the character of a return to the ancestral strain. Moreover, these processes were not detected for four years (2017–2020).

Indexed as

Caliciviridae InfectionsGastroenteritisNorovirusDisease OutbreaksGenetic VariationGenome, ViralGenotypeHumansPhylogenyRussia

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.