ArticleEuropean journal of trauma and emergency surgery : official publication of the European Trauma Society2025
Interpreting traumatic brain injury severity: analysis of the correlation between Glasgow coma scale and abbreviated injury scale.
Article in European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.
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Who cites it
8 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Early Versus Late Initiation of Chemical Venous Thromboembolism Prophylaxis in Adult Patients with Severe Traumatic Brain Injury: A Systematic Review and Meta-analysis.Neurocritical care · 2026Pooled it
- Timing of definitive fracture fixation in patients with concomitant traumatic brain injuries - A systematic review of the literature by the IMPACT group.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2025Pooled it
- [Development and validation of an explainable machine learning-based model for predicting mortality risk in polytrauma patients].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2026Article
- The Effects of Transport Altitude on Outcomes in Traumatic Brain Injury (HEIGHT-TBI): An Observational Cohort Study.Neurocritical care · 2026Article
- Improving mortality prediction in older adults with traumatic brain injury: incorporating neurological and imaging scores into Geriatric Trauma Outcome Score.World journal of emergency medicine · 2026Article
- Unmet Needs for Community-Based Rehabilitation the First 12 Months Postinjury in a Traumatic Brain Injury Population with Moderate-to-Severe Trauma-a Longitudinal Cohort Study.Archives of rehabilitation research and clinical translation · 2026Article
- Extracellular Vesicle and Plasma miRNAs as Candidate Biomarkers of Traumatic Brain Injury in the Context of Polytrauma.International journal of molecular sciences · 2026Article
- Effect of head injury on blood transfusion requirements in severe trauma: a post-hoc analysis of the RESTRIC trial.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2026Article
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Authors and funding
5 authors.
Funding
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Abstract
purposeBoth the Glasgow Coma Scale (GCS) and Abbreviated Injury Scale (AIS) for head injuries quantify traumatic brain injury (TBI) severity. The GCS is based on brain physiology of consciousness, whereas the AIS is an anatomical injury scoring system. This study aimed to describe the correlation of GCS with maximal AIS-Head (maxAIS) and summative AIS-Head (sumAIS) in TBI patients.
methodsData of 4996 adult TBI patients admitted to two level 1 trauma centers in the Netherlands between 2015 and 2021 were selected from the regional trauma registry. The association of GCS with maxAIS and sumAIS was quantified using Spearman rank correlation coefficients (r
resultsFor 39% of the patients, the GCS was not documented in the trauma registry. These patients had less severe head injuries than the 3051 patients with documented GCS scores, who were further analyzed. Among those with severe head injuries (AIS-Head ≥ 4), 53% had a GCS score ≥ 13. The GCS showed a weak inverse relationship with both maxAIS and sumAIS (r
conclusionsThe correlation between physiological alterations (GCS) and anatomical brain damage (AIS) in patients with TBI patients, represented by the GCS and AIS respectively, is weak. Additionally, the GCS appears to underestimate the severity of AIS coded severe TBI. Recognizing this limited correlation is important for valid TBI research.
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