Evidence map›Paper›PMID 40576812›Full record

ArticleHernia : the journal of hernias and abdominal wall surgery2025

Incidence and risk factors for recurrence of incisional hernia repair after liver transplantation: a retrospective cohort study.

Edouard Wasielewski, Thierry Pecot, Estelle Le Pabic, Mohamed Lakehal, Astrid Herrero, Fabien Robin, Karim Boudjema, Laurent Sulpice

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Article in Hernia : the journal of hernias and abdominal wall surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Edouard WasielewskiDepartment of Hepatobiliary and Digestive Surgery, University Hospital, Rennes 1 University, Rennes, France.ORCID 0009-0008-3226-981X
Thierry PecotUniversity of Rennes, Biosit UAR 3480 CNRS- US 018 Inserm, FAIIA core facility, Rennes, F-35000, France.
Estelle Le PabicDepartment of Clinical PharmacologyUniversity Hospital, Rennes 1 University, Rennes, France.
Mohamed LakehalDepartment of Hepatobiliary and Digestive Surgery, University Hospital, Rennes 1 University, Rennes, France.
Astrid HerreroDepartment of HBP Surgery & Transplantation, St-Eloi University Hospital, Montpellier, France.
Fabien RobinDepartment of Hepatobiliary and Digestive Surgery, University Hospital, Rennes 1 University, Rennes, France.
Karim BoudjemaDepartment of Hepatobiliary and Digestive Surgery, University Hospital, Rennes 1 University, Rennes, France.
Laurent SulpiceDepartment of Hepatobiliary and Digestive Surgery, University Hospital, Rennes 1 University, Rennes, France. Laurent.sulpice@chu-rennes.fr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe objective of this study was to evaluate the incidence and identify risk factors associated with the recurrence of incisional hernia (IH) following initial parietal repair in patients who had undergone liver transplantation. Liver transplantation (LT) is a complex procedure associated with numerous complications, particularly those affecting the abdominal wall, with incisional hernia (IH) being the most significant. To date, the risk factors contributing to IH recurrence in this population have not been systematically assessed.

methodsThis retrospective, single-center study included all patients who underwent liver transplantation at Rennes University Hospital between January 1, 2012, and December 31, 2018. The list of eligible patients was provided by the French Biomedicine Agency.

resultsA total of 803 liver transplant recipients were included. Among them, 282 patients (35.1%) developed an incisional hernia (IH) after a median follow-up of 75.87 months [54.7-97.2]. Of these, 50 patients (35.4%) experienced IH recurrence at a median interval of 8.8 months [5.2-34.2] following primary repair. Identified risk factors for recurrence included: length of hospital stay after the initial repair (HR: 1.09 [1.09-1.13], P = < 0.0001), type of repair (suture versus prosthetic) (HR: 2.48 [1.25-4.9], P = 0.009). Visceral obesity is considered a high-risk factor (HR: 2.21 [0.98-4.95], P = 0.055), although the association no longer reached the conventional threshold for statistical significance."

conclusionTo the best of our knowledge, this is the first study to assess body composition as a risk factor for incisional hernia recurrence in the liver transplant population. These findings highlight the importance of considering visceral obesity as a significant predictor of recurrence.

Indexed as

HerniorrhaphyIncisional HerniaLiver TransplantationAdultAgedFemaleFranceHumansIncidenceLength of StayMaleMiddle AgedRecurrenceRetrospective StudiesRisk FactorsIncisional herniaLiver transplantationRecurrenceSkeletal muscle index

Identifiers

PMID40576812
PMCPMC12204869

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.