Evidence map›Paper›PMID 40576721›Full record

ArticleOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2025

Fracture liaison service evaluation during admission for fragility femur fracture increases rates of bone health intervention and outpatient follow-up.

Alex J Demers, Lori S Fitton, Steele M L McCulley, Irving Delgado-Arellanes, Aspen C Miller, Natalie A Glass, J Lawrence Marsh, Michael C Willey

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Article in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Alex J DemersDepartment of Orthopaedics and Rehabilitation, University of Iowa Hospitals and Clinics, 701 W. Forevergreen Road, North Liberty, IA, 52317, USA. alex-demers@uiowa.edu.ORCID http://orcid.org/0000-0002-4568-8764
Lori S FittonDepartment of Orthopaedics and Rehabilitation, University of Iowa Hospitals and Clinics, 701 W. Forevergreen Road, North Liberty, IA, 52317, USA.
Steele M L McCulleyDepartment of Orthopaedics and Rehabilitation, University of Iowa Hospitals and Clinics, 701 W. Forevergreen Road, North Liberty, IA, 52317, USA.
Irving Delgado-ArellanesDepartment of Orthopaedics and Rehabilitation, University of Iowa Hospitals and Clinics, 701 W. Forevergreen Road, North Liberty, IA, 52317, USA.
Aspen C MillerDepartment of Orthopaedics and Rehabilitation, University of Iowa Hospitals and Clinics, 701 W. Forevergreen Road, North Liberty, IA, 52317, USA.
Natalie A GlassDepartment of Orthopaedics and Rehabilitation, University of Iowa Hospitals and Clinics, 701 W. Forevergreen Road, North Liberty, IA, 52317, USA.
J Lawrence MarshDepartment of Orthopaedics and Rehabilitation, University of Iowa Hospitals and Clinics, 701 W. Forevergreen Road, North Liberty, IA, 52317, USA.
Michael C WilleyDepartment of Orthopaedics and Rehabilitation, University of Iowa Hospitals and Clinics, 701 W. Forevergreen Road, North Liberty, IA, 52317, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study evaluates the impact of FLS evaluation during hospital admission for fragility femur fracture on rates of bone health intervention. Patients receiving an inpatient evaluation had higher rates of clinic follow-up, outpatient osteoporosis medication initiation, nutritional supplementation, and DXA acquisition. Inpatient FLS evaluations improve rates of post-injury bone health care. PURPOSE: Fracture liaison services (FLS) can be effective for secondary fracture prevention; however, patient identification and successful follow-up in clinic remain challenging. This study aims to (1) evaluate the impact of FLS evaluation during hospital admission for fragility femur fracture on rates of bone health interventions and outpatient follow-up, (2) compare post-fracture complication rates associated with FLS evaluation, and (3) identify factors predicting outpatient follow-up attendance.

methodsRetrospective review identified patients 50 years and older undergoing operative fixation of a femur fracture at a level I academic trauma center from January 1, 2021, to June 1, 2022. Patients were stratified by inpatient FLS evaluation. Clinic follow-up, DXA acquisition, nutritional interventions, osteoporosis medication initiation, and complications were documented up to 1 year postoperatively. Statistical analyses were performed with an α

resultsTwo hundred thirty-three patients met inclusion criteria, with 54.9% receiving an inpatient FLS evaluation. Patients with an evaluation were more likely to be referred (95% vs. 22%, p < 0.0001) and present (54% vs. 17%, p < 0.0001) to the bone health clinic and have higher rates of vitamin D (95% vs. 41%, p < 0.0001), calcium (88% vs. 35%, p < 0.0001), and protein supplementation (66% vs. 29%, p < 0.0001), DXA acquisition (51% vs. 14%, p < 0.0001), and outpatient osteoporosis medication prescription (38% vs. 17%, p = 0.0003). There was no difference in rates of refracture, subsequent fracture, nonunion, or mortality. Younger patients had increased outpatient clinic attendance.

conclusionInpatient FLS evaluation during hospital admission for fragility femur fracture increases rates of bone health clinic follow-up, osteoporosis intervention, and DXA scan acquisition.

Indexed as

Femoral FracturesOsteoporotic FracturesSecondary PreventionAbsorptiometry, PhotonAftercareAgedAged, 80 and overAmbulatory CareBone DensityBone Density Conservation AgentsDietary SupplementsFemaleFollow-Up StudiesFracture FixationHospitalizationHumansBone Density Conservation AgentsBone healthFemur fractureFracture liaison serviceOsteoporosis

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.