ArticleThe ultrasound journal2025
Accuracy of intracranial pressure assessment with a non-invasive transcranial doppler and arterial blood pressure method in patients with suspected idiopathic intracranial hypertension.
Article in The ultrasound journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Novel and classic imaging signs of increased intracranial pressure.Neuroradiology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe incidence of idiopathic intracranial hypertension (IIH) has nearly doubled in the recent decade, possibly due to increasing obesity rates. Lumbar puncture pressure (LPP) assessment is still the diagnostic gold standard but due to invasiveness of the method, several non-invasive alternatives exist. We evaluated a non-invasive intracranial pressure (nICP) method for its accuracy to predict LPP.
methodsProspectively, we included patients with suspected IIH and obtained nICP by means of a combined bilateral transcranial Doppler and photoplethysmographic arterial blood pressure method. In addition, we searched for an empty sella sign by magnetic resonance tomography and evaluated the optical nerve sheath diameter (ONSD) bilaterally by Duplex sonography. We analyzed data on an individual level for their capability to predict LPP. Included were 70 patients from which 60 with a complete data set were used for further evaluation. Patients with symptomatic intracranial pressure were excluded.
resultsThe nICP and LPP correlated with R = 0.85 on the right, and R = 0.79 on the left side (p < 0.001, respectively). The mean difference of nICP-LPP was 0.45 ± 4.93 cmH2O. Its sensitivity to predict an increased ICP was 0.92, the specificity was 0.88 and negative predictive value 0.88. The empty sella sign and the ONSD showed no significant correlation to the LPP.
conclusionThe nICP method allows pre-diagnosis of increased ICP and might help in decision making for the need of LPP. Due to the moderately increased ICP levels, ONSD remained insignificant.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.