Evidence map›Paper›PMID 40576413›Full record

ArticleAnnals of African medicine2026

Proportion of Avascular Necrosis of Femoral Head in Coronavirus Disease 19 Patients.

Premjit R Sujir, Keerthan Ranga Nayak, Aayush Singh

Abstract read
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Article in Annals of African medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

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1citing papers in PubMed, 1 pooled it
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1 · What the graph read from it

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3 · Its place in the literature

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1 citing paper in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Premjit R SujirDepartment of Orthopaedics, Kasturba Medical College Mangalore, Manipal Academy of Higher Education, Manipal, Karnataka, India.
Keerthan Ranga Nayak
Aayush Singh

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesClarify the distinctive characteristics of avascular necrosis of the femoral head (AVNFH) in relation to coronavirus disease 19 (COVID-19) and report the successive individuals who were identified with the condition after recovering from COVID-19. MATERIALS AND

methodsFrom August 2023 to July 2024, we examined 24 successive patients (35 hips) prospectively who received an AVNFH diagnosis after recovering from COVID-19. Twenty patients were on corticosteroids for the treatment of COVID-19. The staging of AVNFH was decided by plain radiographs and magnetic resonance imaging. An association between the stage with the dosage of steroids and the comorbidities was evaluated.

resultsAfter COVID-19, hip symptoms took a mean of 6.13 months to manifest. In Methylprednisolone equivalent, the average steroid dosage was 713.2 mg. For those on steroid medication, the mean time for COVID-19 before hip complaints was 5.95 months. It was discovered that the mean COVID-19 period before the onset of hip symptoms was 7.125 months for individuals without comorbidities and 3 months for those with both diabetes and hypertension.

conclusionThere has been an increase in AVN during the pandemic. This rise is probably because patients with COVID-19 pneumonia were receiving severe doses of corticosteroids. There is also an increase in severity and decrease in the duration of COVID-19 before hip symptoms in patients with comorbidities like diabetes. Given the minimal total amount of steroids taken by our patients, it is possible that vasculitis-associated COVID-19 contributes to the pathophysiology of AVN of the femur head.

Indexed as

Adrenal Cortex HormonesCOVID-19Femur Head NecrosisAdultAgedComorbidityCOVID-19 Drug TreatmentFemaleGlucocorticoidsHumansMagnetic Resonance ImagingMaleMethylprednisoloneMiddle AgedProspective StudiesSARS-CoV-2Adrenal Cortex HormonesGlucocorticoidsMethylprednisoloneAvascular necrosis of femoral headcoronavirus disease 19corticostéroïdescorticosteroidsmaladie du coronavirus 19Nécrose avasculaire de la tête fémoraleSARSSRASvascularitevasculitis

Identifiers

PMID40576413
PMCPMC12872148

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.