Evidence map›Paper›PMID 40576317›Full record

ArticleTranslational behavioral medicine2025

Clinical effectiveness of best-evidence cancer distress management in a real-world practice setting.

Shawna L Ehlers, Janae L Kirsch, Elizabeth L Kacel, Lisa M Gudenkauf, Sherrie M Hanna, Eleshia J Morrison, Jill Snuggerud, Jeffrey P Staab, Katharine A R Price, Andrea E Wahner Hendrickson and 5 more

Abstract read
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In one paragraph

Article in Translational behavioral medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Shawna L EhlersDepartment of Psychiatry and Psychology, Mayo Clinic, 200 1st St SW, Rochester, MN 55902, USA.ORCID 0000-0003-3004-5966
Janae L KirschDepartment of Psychiatry and Psychology, Mayo Clinic, 200 1st St SW, Rochester, MN 55902, USA.ORCID 0000-0003-3041-9518
Elizabeth L KacelDepartment of Psychiatry and Psychology, Mayo Clinic, 200 1st St SW, Rochester, MN 55902, USA.
Lisa M GudenkaufDepartment of Psychiatry and Psychology, Mayo Clinic, 200 1st St SW, Rochester, MN 55902, USA.
Sherrie M HannaDepartment of Psychiatry and Psychology, Mayo Clinic, 200 1st St SW, Rochester, MN 55902, USA.
Eleshia J MorrisonDepartment of Psychiatry and Psychology, Mayo Clinic, 200 1st St SW, Rochester, MN 55902, USA.
Jill SnuggerudDepartment of Psychiatry and Psychology, Mayo Clinic, 200 1st St SW, Rochester, MN 55902, USA.
Jeffrey P StaabDepartment of Psychiatry and Psychology, Mayo Clinic, 200 1st St SW, Rochester, MN 55902, USA.
Katharine A R PriceDepartment of Oncology, Mayo Clinic, 200 1st St SW, Rochester, MN 55902, USA.
Andrea E Wahner HendricksonDepartment of Oncology, Mayo Clinic, 200 1st St SW, Rochester, MN 55902, USA.
Carrie BronarsDepartment of Psychiatry and Psychology, Mayo Clinic, 200 1st St SW, Rochester, MN 55902, USA.
Kristine A DonovanDepartment of Psychiatry and Psychology, Mayo Clinic, 200 1st St SW, Rochester, MN 55902, USA.
Deanna HofschulteDepartment of Psychiatry and Psychology, Mayo Clinic, 200 1st St SW, Rochester, MN 55902, USA.
Holly C EdwardsDepartment of Psychiatry and Psychology, Mayo Clinic, 200 1st St SW, Rochester, MN 55902, USA.
Kathryn J RuddyDepartment of Oncology, Mayo Clinic, 200 1st St SW, Rochester, MN 55902, USA.

Funding

Mayo Clinic CTSA UL1TR002377NCATS NIH HHSNIH HHS
6 · The paper itself

Abstract

backgroundDespite 40 years of evidence supporting psychosocial interventions as a component of comprehensive cancer care, patients continue to report vast unmet psychosocial needs and distress. Cognitive behavioral therapies for cancer distress (CBT-C) are the most rigorously tested class of psychosocial interventions for cancer care. PURPOSE: To report clinical effectiveness outcomes of cancer-related distress and self-efficacy following implementation of best-evidence CBT-C, adapted for a real-world, billable practice setting.

methodsPatients who completed group-delivered, CBT-C (10 intervention hours, 5 sessions) in the practice setting were invited to enroll in a research study to document cancer distress across the year following CBT-C. Participants (n = 65) were primarily middle-aged (mean 50.5 years, 17% were young adults ≤40 years), female, and White. Analyses utilized mixed linear models with intent-to-treat procedures. Given group delivery and social skills training content within CBT-C, social self-efficacy was assessed as a potential treatment mechanism.

resultsDistress decreased across the year following CBT-C (mean score change of 20 points for YAs, 6 points for non-YAs), with statistically significant age x time effects. Within-person improvements in social self-efficacy scores were related to reductions in cancer distress, including distress subscales of intrusive thoughts, avoidant coping, and hyperarousal. The model explained 76.6% of the total variance in cancer distress.

conclusionsThis study demonstrates the effective translation of CBT-C from controlled research trials to the practice setting. CBT-C effectiveness within a mixed-cancer population and relatively rural region of the US is also supported. CBT-C can be effectively translated to the practice settings for which it is intended.

Indexed as

Cognitive Behavioral TherapyNeoplasmsPsychological DistressStress, PsychologicalAdultAgedFemaleHumansMaleMiddle AgedSelf EfficacyTreatment Outcomebehavioral interventioncancercancer distresscognitive behavioral therapyoncologyyoung adult

Identifiers

PMID40576317
PMCPMC12203546

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.