Evidence map›Paper›PMID 40576249›Full record

ArticleInternal medicine journal2025

Clinical outcomes of patients seen by psychiatrists in a multidisciplinary clinic for disorders of gut-brain interaction.

Evangelia Dendrinos, Hannah Kim, Daniel Hubik, Jessica Green, Linda Yang, Annalise Stanley, Michael Salzberg, Michael A Kamm, Chamara Basnayake

Abstract read
In one paragraph

Article in Internal medicine journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Evangelia DendrinosDepartment of Gastroenterology, St Vincent's Hospital Melbourne, Melbourne, Victoria, Australia.
Hannah KimDepartment of Gastroenterology, St Vincent's Hospital Melbourne, Melbourne, Victoria, Australia.
Daniel HubikPeter MacCallum Cancer Centre, Melbourne, Victoria, Australia.
Jessica GreenDepartment of Gastroenterology, St Vincent's Hospital Melbourne, Melbourne, Victoria, Australia.
Linda YangDepartment of Gastroenterology, St Vincent's Hospital Melbourne, Melbourne, Victoria, Australia.
Annalise StanleyDepartment of Gastroenterology, St Vincent's Hospital Melbourne, Melbourne, Victoria, Australia.
Michael SalzbergDepartment of Psychiatry, University of Melbourne, Melbourne, Victoria, Australia.
Michael A KammDepartment of Gastroenterology, St Vincent's Hospital Melbourne, Melbourne, Victoria, Australia.ORCID 0000-0003-3319-7199
Chamara BasnayakeDepartment of Gastroenterology, St Vincent's Hospital Melbourne, Melbourne, Victoria, Australia.ORCID 0000-0001-6103-769X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPatients with disorders of gut-brain interaction (DGBIs) presenting to specialist care have a high prevalence of psychiatric morbidity. Psychiatrists can provide effective treatments for these disorders; however, care is rarely delivered in an integrated manner.

aimsThis study aimed to characterise patients seen by psychiatrists in a multidisciplinary gastrointestinal (GI) clinic, describe the treatment provided and examine clinical outcomes.

methodsIn a single-centre multidisciplinary gastroenterology clinic, clinical records were retrospectively evaluated for patients with DGBIs seen by a psychiatrist. Patient demographics, medical and psychiatric history, records of adverse childhood experiences (ACEs) and adult trauma were collected. GI and mental health symptom outcomes were assessed using a five-point scale.

resultsNinety-seven patients (median age, 35 years; 77% female) were seen by the psychiatrist (median treatment duration 2.5 months) between January 2017 and November 2021. Fifty-six per cent had irritable bowel syndrome and 18% had functional dyspepsia. Common psychiatric comorbidities were anxiety (51%) and depression (43%). Seventy-seven per cent had a history of ACEs and 26% had a history of sexual trauma. Seventy-five per cent had previously seen a psychiatrist or psychologist. DGBI-Clinic psychiatrists provided a range of treatments including psychoeducation (64%), insight-oriented psychotherapy (39%), medication changes (27%) and cognitive behavioural therapy (19%). A majority of patients had improvement (46%) or resolution (11%) in GI symptoms. Forty per cent experienced improvement in mental health symptoms. Improvement in GI and mental health symptoms were correlated (P = 0.002).

conclusionsA majority of patients with DGBI who were seen by psychiatrists within a multidisciplinary clinic demonstrated improvement in GI and mental health symptoms.

Indexed as

Brain-Gut AxisGastrointestinal DiseasesMental DisordersPsychiatryAdultAgedFemaleHumansMaleMiddle AgedPsychiatristsRetrospective StudiesTreatment OutcomeYoung Adultfunctional gastrointestinal disordersintegrated careirritable bowel syndromepsychiatrypsychosomatic disorders

Identifiers

PMID40576249
PMCPMC12515468

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.