Evidence map›Paper›PMID 40576238›Full record

ArticleASAIO journal (American Society for Artificial Internal Organs : 1992)2026

Direct Cardiac Compression Device for Short-Term Mechanical Circulatory Support.

Kristof Sarosi, Thomas Kummer, Stijn Vandenberghe, Stefanos Demertzis, Patrick Jenny

Abstract read
In one paragraph

Article in ASAIO journal (American Society for Artificial Internal Organs : 1992), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kristof SarosiFrom the Institute of Fluid Dynamics, Department of Mechanical and Process Engineering, ETH Zurich, Zurich, Switzerland.ORCID 0009-0006-1197-5956
Thomas KummerFrom the Institute of Fluid Dynamics, Department of Mechanical and Process Engineering, ETH Zurich, Zurich, Switzerland.
Stijn VandenbergheCardiovascular Engineering, Cardiocentro Ticino Institute, Ente Ospedaliero Cantonale, Lugano, Switzerland.
Stefanos DemertzisFaculty of Biomedical Sciences, Università della Svizzera italiana, Lugano, Switzerland.
Patrick JennyFrom the Institute of Fluid Dynamics, Department of Mechanical and Process Engineering, ETH Zurich, Zurich, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients requiring short-term ventricular assistance have limited options. While not all interventions necessarily require blood-contacting support, all current devices are invasive and interact with the bloodstream. Direct cardiac compression (DCC) devices offer a potential solution by providing mechanical circulatory support (MCS) without contact with the bloodstream. This proof-of-concept study compares a novel DCC patch device for short-term MCS to open-chest cardiac compression (OCCC) using an ex vivo ovine cardiac arrest (CA) heart model. Performance is evaluated by assessing pressure, flow rate, and valve functionality, as well as any damage to the tissue. In the CA model, the device achieves 1.5 L/min cardiac output and a mean aortic pressure of 55 mm Hg. Despite direct epicardial contact, the DCC patch device maintains effective valve function. This study demonstrates that the DCC patch device achieves comparable performance to OCCC, supporting previous in vitro findings. Our results suggest the potential for this novel DCC patch device to be applied across a range of short-term MCS scenarios.

Indexed as

Heart ArrestHeart-Assist DevicesAnimalsSheepcardiac arrestdirect cardiac compressionemergency heart surgerymechanical circulatory supportventricular assist device

Identifiers

PMID40576238
PMCPMC13218586

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.