Evidence map›Paper›PMID 40575937›Full record

SynthesisNeurourology and urodynamics2026

Role of Gynecologic Findings in Interstitial Cystitis/Bladder Pain Syndrome: A Consensus.

Marie E Sullivan, Amr El Haraki, Anna Padoa, Katy Vincent, Kristene E Whitmore, Mauro Cervigni

Abstract readSystematic ReviewConsensus Statement
In one paragraph

Synthesis in Neurourology and urodynamics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Marie E SullivanWake Forest University, Winston Salem, North Carolina, USA.ORCID https://orcid.org/0000-0002-2847-5249
Amr El HarakiWake Forest University, Winston Salem, North Carolina, USA.ORCID https://orcid.org/0000-0001-8412-5967
Anna PadoaChaim Sheba Medical Center, Ramat Gan, Israel.ORCID https://orcid.org/0000-0002-9032-3852
Katy VincentNuffield Department of Women's & Reproductive Health, University of Oxford, Oxford, UK.ORCID https://orcid.org/0000-0001-9249-2492
Kristene E WhitmoreVirtua Health, Drexel University, Cherry Hill, New Jersey, USA.
Mauro CervigniDepartment Urology, Referral Center Interstitial Cystitis, "La Sapienza", University of ICOT, Latina, Italy.ORCID https://orcid.org/0000-0003-4071-4393

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the role of gynecologic findings in Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS) by reviewing current international guidelines and identifying relevant gynecologic co-morbidities.

methodsThis consensus statement was developed through a systematic four-phase process: (1) comprehensive literature review across PubMed/MEDLINE, Embase, Cochrane Library, and Web of Science databases (inception-January 2025) using predefined search terms related to IC/BPS and gynecologic conditions; (2) assembly of a 6-member multidisciplinary expert panel including urologists, urogynecologists, gynecologists and pain specialists; (3) consensus development via modified Delphi technique comprising several electronic rating rounds and a face-to-face meeting, with consensus defined as ≥ 80% agreement; and (4) manuscript preparation with iterative review.

resultsA number of associated gynecologic disorders may overlap with IC/BPS, our consensus committee identified five main co-morbid disorders: Endometriosis/Adenomyosis, Genito-Pelvic Pain Penetration Disorder/Sexual Dysfunction, Overactive Pelvic Floor Muscles, Hormone- Associated Genitourinary Changes, Vulvodynia/Vestibulodynia.

conclusionWhile not exhaustive, this consensus highlights the most prevalent gynecologic co-morbidities supported by current literature. Clinical evaluation should prioritize a detailed medical history and pelvic examination to identify these overlapping conditions. Future directions include developing a multidisciplinary diagnostic and treatment algorithm to guide clinicians-including urologists, gynecologists, urogynecologists, physical therapists-in comprehensive IC/BPS care.

Indexed as

Cystitis, InterstitialGenital Diseases, FemalePelvic PainComorbidityFemaleHumansbladder pain syndromeendometriosisgynecologic comorbiditiesinterstitial cystitismultidisciplinary carepelvic floor dysfunctionvulvodynia

Identifiers

PMID40575937
PMCPMC12748013

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.