Evidence map›Paper›PMID 40575641›Full record

ArticleWorld journal of virology2025

Synergistic efficacy of phages along with vancomycin for eradication of vancomycin-resistant

Minakshi Sahu, Ranjeet Kumar Vishwakarma, Subhash Lal Karn, Gopal Nath

Abstract read
In one paragraph

Article in World journal of virology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Minakshi SahuDepartment of Microbiology, Institute of Medical Sciences, Banaras Hindu University, Varanasi 221005, India.
Ranjeet Kumar VishwakarmaDepartment of Physiology, Institute of Medical Sciences, Banaras Hindu University, Varanasi 221005, India.
Subhash Lal KarnDepartment of Microbiology, Institute of Medical Sciences, Banaras Hindu University, Varanasi 221005, India.
Gopal NathDepartment of Microbiology, Institute of Medical Sciences, Banaras Hindu University, Varanasi 221005, India. gopalnath@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe upsurge of antibiotic resistance is a significant challenge to public health, and the dry pipeline of new antibiotics has prompted the discovery of alternative treatment approaches.

aimTo optimize the doses, order, and timing to optimize the synergy of phages and vancomycin on different bacteria states.

methodsA volume of 180 μL of

resultsThe biofilm model demonstrated that combining phages with vancomycin can eradicate the biofilm. Sequential therapy, involving phage application 8 hours before the antibiotic at a concentration of 10

conclusionThe combination of phage ɸEFP01 at a higher concentration with a subinhibitory concentration of vancomycin yields a synergistic antibacterial outcome on

Indexed as

BacteriophageBiofilmEnterococcus faecalisMultiple drug resistancePhage-antibiotic synergy

Identifiers

PMID40575641
PMCPMC12188910

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.