Evidence map›Paper›PMID 40575585›Full record

ArticleAging and health research2025

Contribution of chronic conditions to mortality: Differences by race and ethnicity.

Miriam R Elman, Ana R Quiñones, Gail J McAvay, Brent Vander Wyk, Corey L Nagel, Heather G Allore

Abstract read
In one paragraph

Article in Aging and health research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Miriam R ElmanOHSU-PSU School of Public Health, 1810 SW 5th Avenue, OR 97201, United States.
Ana R QuiñonesOHSU-PSU School of Public Health, 1810 SW 5th Avenue, OR 97201, United States.
Gail J McAvayDepartment of Internal Medicine, Yale School of Medicine, 300 George Street 7th Floor, New Haven, CT 06510, United States.
Brent Vander WykDepartment of Internal Medicine, Yale School of Medicine, 300 George Street 7th Floor, New Haven, CT 06510, United States.
Corey L NagelCollege of Nursing, University of Arkansas for Medical Sciences, 4301 West Markham Street, Little Rock, AR 72205, United States.
Heather G AlloreDepartment of Internal Medicine, Yale School of Medicine, 300 George Street 7th Floor, New Haven, CT 06510, United States.

Funding

Yale Study Support Suite (YES3): Dashboard and Web Portal Software Supporting Research Workflow through integrated, customizable REDCap External ModulesP30AG021342 · NIA · YALE UNIVERSITY · PI Albert C Shaw · 2002 to 2026
$37.9M
Yale Alzheimer Disease Research CenterP30AG066508 · NIA · YALE UNIVERSITY · PI STEPHEN M STRITTMATTER, CHRISTOPHER H VAN DYCK · 2020 to 2026
$30.2M
Preparing For What Is Next With Aducanumab In Real World SettingsR33AG057806 · NIA · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI Christopher Barrett Bowling, Ana Roman Quinones · 2018 to 2026
$9.0M
Multimorbidity Combinations and Dementia Onset Among Race/Ethnic Older AdultsRF1AG058545 · NIA · OREGON HEALTH & SCIENCE UNIVERSITY · PI QUINONES, ANA ROMAN · 2019 to 2019
$3.6M
Advancing Geriatrics Infrastructure & Network Growth - Admin Supplement: Designing and Testing an Informatics Tool to Aid Prescribers in Reducing Anticholinergic Burden in Older AdultsR24AG045050 · NIA · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI GURWITZ, JERRY H · 2014 to 2017
$3.6M
Changes in Multimorbidity and Disability Among Race/Ethnic Older Adults (Administrative Supplement)R01AG055681 · NIA · OREGON HEALTH & SCIENCE UNIVERSITY · PI QUINONES, ANA ROMAN · 2017 to 2021
$2.8M
NIA NIH HHS P30 AG021342NIA NIH HHS P30 AG066508NIA NIH HHS R01 AG055681NIA NIH HHS R24 AG045050NIA NIH HHS R33 AG057806NIA NIH HHS RF1 AG058545
6 · The paper itself

Abstract

Background: Racial and ethnic health disparities are persistent in the United States. The accumulation of chronic conditions and mortality are important contributors to these observed inequities. Methods: We assessed the contribution of coexisting conditions to mortality among Hispanic, non-Hispanic White, and non-Hispanic Black older adults born in the United States. We used nationally-representative data from the Health and Retirement Study (HRS) from 1998-2020 ( Results: Death occurred in 42.2 % (95 % confidence interval [CI]=37.4, 47.0) of Hispanic, 42.7 % (95 % CI=41.7, 44.2) of White, and 46.4 % (95 % CI=42.7, 50.1) of Black respondents. The eight conditions increasing the risk of death contributed 73.9 % (95 % CI=50.7, 100.0) of mortality events among Hispanic respondents, 66.2 % (95 % CI=48.9, 81.5) among Black respondents, and 57.7 % (95 % CI=52.1, 62.5) among White respondents. Dementia had the strongest association with mortality with an adjusted odds ratio of 3.23 for Hispanic (95 % CI=1.90, 5.49), 3.14 for White (95 % CI=2.61, 3.78), and 2.11 for Black (95 % CI=1.63, 2.73) respondents. The development and progression of cancer malignancies contributed most to mortality for White adults. In contrast, hypertension, contributed most to mortality for Hispanic and Black adults. Conclusions: Hispanic, Black, and White Americans differed in the prevalence and incidence of chronic conditions, as well as their association with mortality. Together, these conditions resulted in contributions to mortality that varied substantially.

Indexed as

AgingAttributable fractionMortalityMultimorbidityRace/ethnicity

Identifiers

PMID40575585
PMCPMC12199773

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.