ArticleJournal of education and health promotion2025
Impact of obesity on serum markers of prostatic disorders: A cross-sectional study in Iraqi.
Article in Journal of education and health promotion, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
The aim in the current research was to assess the correlation between body mass index (BMI) and two prostatic markers-total prostate-specific antigen (tPSA) and free prostate-specific antigen (fPSA). A prospective randomized cross-sectional study involved 127 Iraqi men (40 years or older). The exclusion criteria were baseline PSA levels ≥5ng/ml, prostate cancer, and the use of medications that could alter the levels of prostate-specific markers. All participants underwent blood sampling for analysis. Anthropometric measurements, including height, weight, and BMI, were studied. The levels of total and free prostate-specific antigens (tPSA and fPSA) were measured using the ELISA test and immune-enzymometric method. Study consisted of 26 patients (20.47%) with a normal BMI, 47 overweight-37%, 33 patients-obesity (25.98%), and 21 men-severe obesity (16.53%). The mean values (±standard deviation) of the prostate-specific markers tPSA and fPSA were 1.683 ± 0.563 ng/ml and 0.537 ± 0.189 ng/ml, respectively. The study of apparently healthy Iraqi men and obese patients, no statistically significant relationship was found between BMI and the levels of the prostate-specific markers tPSA and fPSA. These findings suggest that BMI may not be a reliable predictor of these prostatic markers in the studied sample.
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