ArticleWorld journal of gastrointestinal pharmacology and therapeutics2025
Disease characteristics and long-term outcomes of cyclic vomiting syndrome in Singaporean children.
Article in World journal of gastrointestinal pharmacology and therapeutics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundCyclic vomiting syndrome (CVS) and its effect on nutritional status has not been well described.
aimTo describe the clinical characteristics, treatment and outcomes of children with CVS in Singapore.
methodsRetrospective cohort study of pediatric patients aged 1 to 18 years old with CVS diagnosed at KK Women's and Children's Hospital in Singapore from 2011 to 2021.
resultsThirty-two children (69% female) with CVS were included in the study, with mean age of onset of symptoms at 7 (± 4) years and mean follow up duration of 5 years. Forty percent (12/32) of patients were underweight at diagnosis with no other identifiable organic cause, with a median body mass index (BMI)
conclusionProphylactic treatment is effective in improving nutritional status as well as reducing symptom frequency and should be considered for patients with complications such as growth failure and significant hypertension.
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