Evidence map›Paper›PMID 40575355›Full record

ReviewJournal of tissue engineering

Advances in hydrogels for capturing and neutralizing inflammatory cytokines.

Hongwei Qin, Ze Li, Sicheng Li, Jinjian Huang, Jianan Ren, Xiuwen Wu

Abstract readReview
In one paragraph

Review in Journal of tissue engineering. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Hybrid Hydrogels in Pain Management Application: A Comprehensive Review.Clinical pharmacology : advances and applications · 2026
    Review
  7. Review
  8. 3D Bioprinting Strategies in Autoimmune Disease Models.International journal of molecular sciences · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hongwei QinThe First Hospital of AUST, Anhui University of Science and Technology, Huainan, China.ORCID https://orcid.org/0009-0000-8447-7663
Ze LiResearch Institute of General Surgery, Jinling Hospital, Affiliated Hospital of Medical School, Nanjing University, China.ORCID https://orcid.org/0000-0002-2818-4396
Sicheng LiResearch Institute of General Surgery, Jinling Hospital, Affiliated Hospital of Medical School, Nanjing University, China.ORCID https://orcid.org/0009-0008-7428-8867
Jinjian HuangResearch Institute of General Surgery, Jinling Hospital, Affiliated Hospital of Medical School, Nanjing University, China.ORCID https://orcid.org/0000-0002-8951-8935
Jianan RenThe First Hospital of AUST, Anhui University of Science and Technology, Huainan, China.ORCID https://orcid.org/0000-0001-9011-3989
Xiuwen WuThe First Hospital of AUST, Anhui University of Science and Technology, Huainan, China.ORCID https://orcid.org/0000-0002-3813-3867

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inflammatory cytokines play a crucial role in the inflammatory response, and their aberrant expression and overproduction are closely associated with the development of many diseases. However, traditional inflammation treatment strategies are often accompanied by serious side effects, limiting their widespread use. In recent years, hydrogel, as a material with a three-dimensional network structure, good biocompatibility and modulability, has great potential for trapping and neutralizing inflammatory factors. Hydrogels can capture and neutralize inflammatory cytokines through various mechanisms such as electrostatic interactions, coupling with cytokine antibodies or binding nanoparticles. In addition, hydrogel microspheres, an important form of hydrogels, have excellent broad-spectrum binding of inflammatory cytokines in combination schemes with cell membranes. This article reviews recent research advances in hydrogel capture and neutralization of inflammatory cytokines, discussing the advantages of various mechanisms and their applications in different diseases. Overall, we believe that hydrogels are expected to further advance the development of therapeutic modalities for inflammatory diseases in the future.

Indexed as

cytokine capturecytokine neutralizationhydrogelinflammatory cytokine

Identifiers

PMID40575355
PMCPMC12198567

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.