Evidence map›Paper›PMID 40575318›Full record

ArticleJACS Au2025

Light-Induced Synthesis and Radiotheranostic Treatment of Gastric Cancer with

Patrick A Cieslik, Dominik Roth, Eda Nisli, Jonas Genz, Cesare Berton, Pascal V Grundler, Colin C Hillhouse, Anzhelika N Moiseeva, Mirja Nolff, Henrik Braband and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in JACS Au, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Patrick A CieslikDepartment of Chemistry, University of Zurich, Winterthurerstrasse 190, CH-8057 Zurich, Switzerland.ORCID https://orcid.org/0000-0002-9709-3711
Dominik RothDepartment of Chemistry, University of Zurich, Winterthurerstrasse 190, CH-8057 Zurich, Switzerland.
Eda NisliDepartment of Chemistry, University of Zurich, Winterthurerstrasse 190, CH-8057 Zurich, Switzerland.
Jonas GenzDepartment of Chemistry, University of Zurich, Winterthurerstrasse 190, CH-8057 Zurich, Switzerland.
Cesare BertonDepartment of Chemistry, University of Zurich, Winterthurerstrasse 190, CH-8057 Zurich, Switzerland.
Pascal V GrundlerPaul Scherrer Institute PSI, Forschungsstrasse 111, CH-5232 Villigen, Switzerland.
Colin C HillhousePaul Scherrer Institute PSI, Forschungsstrasse 111, CH-5232 Villigen, Switzerland.
Anzhelika N MoiseevaPaul Scherrer Institute PSI, Forschungsstrasse 111, CH-5232 Villigen, Switzerland.
Mirja NolffKlinik für Kleintierchirurgie, Vetsuisse-Fakultät, University of Zurich, Winterthurerstrasse 260, CH-8057 Zurich, Switzerland.
Henrik BrabandDepartment of Chemistry, University of Zurich, Winterthurerstrasse 190, CH-8057 Zurich, Switzerland.
Nicholas P van der MeulenPaul Scherrer Institute PSI, Forschungsstrasse 111, CH-5232 Villigen, Switzerland.
Jason P HollandDepartment of Chemistry, University of Zurich, Winterthurerstrasse 190, CH-8057 Zurich, Switzerland.ORCID https://orcid.org/0000-0002-0066-219X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Radiolabeled monoclonal antibodies (mAbs) form a major branch of nuclear medicine and are used in the development of tracers for both diagnostic imaging and molecularly targeted radio-(immuno)-therapy (RIT). Since treatment options for many types of late-stage cancers are limited and these diseases become refractory to classic chemotherapy, new tools are required to improve patient outcomes. The high tumor uptake and specificity of mAbs, coupled with increased therapeutic range of energetic β

Indexed as

gastric cancerhepatocyte growth-factor receptor (c-MET)onartuzumabphotochemistryradiochemistryradioimmunotherapyterbium-161

Identifiers

PMID40575318
PMCPMC12188480

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.