Evidence map›Paper›PMID 40575315›Full record

ArticleJACS Au2025

Dual-Enzyme-Mimicking Sites in Covalent Organic Frameworks Enable Highly Efficient Relay Electrosynthesis of Ammonia.

Si-Wen Ke, Yang Lv, Yuming Gu, Jian Su, Lingyu Tang, Lincan Fang, Shuai Yuan, Jing Ma, Mengning Ding, Jing-Lin Zuo

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in JACS Au, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Pd-Cu Single-Atom Catalysts in Covalent Organic Frameworks for Sonogashira Cross-Coupling Reaction.Chemistry of materials : a publication of the American Chemical Society · 2026
    Article
  3. Enzyme-Integrated Hydrogels for Advanced Biological Applications.Polymer science & technology (Washington, D.C.) · 2026
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Si-Wen KeState Key Laboratory of Coordination Chemistry, Key Laboratory of Mesoscopic Chemistry of MOE, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing, Jiangsu 210023, P. R. China.
Yang LvState Key Laboratory of Coordination Chemistry, Key Laboratory of Mesoscopic Chemistry of MOE, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing, Jiangsu 210023, P. R. China.ORCID https://orcid.org/0000-0002-5885-6659
Yuming GuState Key Laboratory of Coordination Chemistry, Key Laboratory of Mesoscopic Chemistry of MOE, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing, Jiangsu 210023, P. R. China.ORCID https://orcid.org/0000-0003-1366-831X
Jian SuState Key Laboratory of Coordination Chemistry, Key Laboratory of Mesoscopic Chemistry of MOE, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing, Jiangsu 210023, P. R. China.ORCID https://orcid.org/0000-0002-1200-4709
Lingyu TangState Key Laboratory of Coordination Chemistry, Key Laboratory of Mesoscopic Chemistry of MOE, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing, Jiangsu 210023, P. R. China.
Lincan FangCollege of Chemistry and Materials Science, Key Laboratory of Functional Molecular Solids, Ministry of Education, Anhui Laboratory of Molecule-Based Materials, Anhui Key Laboratory of Functional Molecular Solids, Anhui Normal University, 189 Jiuhua Southern Road, Wuhu 241002, P. R. China.
Shuai YuanState Key Laboratory of Coordination Chemistry, Key Laboratory of Mesoscopic Chemistry of MOE, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing, Jiangsu 210023, P. R. China.ORCID https://orcid.org/0000-0003-3329-0481
Jing MaState Key Laboratory of Coordination Chemistry, Key Laboratory of Mesoscopic Chemistry of MOE, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing, Jiangsu 210023, P. R. China.ORCID https://orcid.org/0000-0001-5848-9775
Mengning DingState Key Laboratory of Coordination Chemistry, Key Laboratory of Mesoscopic Chemistry of MOE, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing, Jiangsu 210023, P. R. China.ORCID https://orcid.org/0000-0001-6581-3385
Jing-Lin ZuoState Key Laboratory of Coordination Chemistry, Key Laboratory of Mesoscopic Chemistry of MOE, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing, Jiangsu 210023, P. R. China.ORCID https://orcid.org/0000-0003-1219-8926

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Electrocatalytic nitrate reduction poses significant importance in green ammonia synthesis and water denitrification. To date, high-performance nitrate reduction still relies on noble-metal-based catalysts, while transition metal compound and framework catalysts generally suffer from low activities (in terms of turnover frequency values), leading to insufficient ability to rapidly process large amounts of nitrate at the industrial level. To this end, enzyme-mimicking catalytic systems that integrate the high TOF efficiency of enzymatic sites (typically with nonprecious metal centers) into the crystalline, orderly assembled, and porous molecular frameworks hold great theoretical promises, yet the search for any single enzyme-site mimics has failed to overcome current limitations. Herein, we demonstrate the rational design of a series of covalent organic frameworks (COFs) to incorporate periodically alternating metalloporphyrin and metal-bis-(dithiolene), respectively mimicking nitrate reductase and nitrite reductase enzymes, as a dual functional assembly. The dual-enzyme-mimicking Ni-TAPP-Cu boosts the electrocatalytic activity of NO

Indexed as

ammonia electrosynthesiscovalent organic frameworksdual-enzyme-mimickingnitrate reductionnon-noble-metal

Identifiers

PMID40575315
PMCPMC12188482

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.