Evidence map›Paper›PMID 40575313›Full record

ArticleJACS Au2025

Artificial Tyroserleutide Transporters for Synergistic Cancer Therapy.

Daoxin Luo, Chunyan Jia, Xinghan Zhu, Jin Zhou, Pengzhe Li, Juncheng Wan, Qing Yang, Rong Ding, Xiang Gao, Zhiping Zeng and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in JACS Au, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Daoxin LuoFujian Provincial Key Laboratory of Innovative Drug Target Research, State Key Laboratory of Vaccines for Infectious Diseases, Xiang An Biomedicine Laboratory, MOE Key Laboratory of Spectrochemical Analysis and Instrumentation, School of Pharmaceutical Sciences, Xiamen University, Xiamen, Fujian 361102, China.
Chunyan JiaFujian Provincial Key Laboratory of Innovative Drug Target Research, State Key Laboratory of Vaccines for Infectious Diseases, Xiang An Biomedicine Laboratory, MOE Key Laboratory of Spectrochemical Analysis and Instrumentation, School of Pharmaceutical Sciences, Xiamen University, Xiamen, Fujian 361102, China.
Xinghan ZhuFujian Provincial Key Laboratory of Innovative Drug Target Research, State Key Laboratory of Vaccines for Infectious Diseases, Xiang An Biomedicine Laboratory, MOE Key Laboratory of Spectrochemical Analysis and Instrumentation, School of Pharmaceutical Sciences, Xiamen University, Xiamen, Fujian 361102, China.
Jin ZhouFujian Provincial Key Laboratory of Innovative Drug Target Research, State Key Laboratory of Vaccines for Infectious Diseases, Xiang An Biomedicine Laboratory, MOE Key Laboratory of Spectrochemical Analysis and Instrumentation, School of Pharmaceutical Sciences, Xiamen University, Xiamen, Fujian 361102, China.
Pengzhe LiFujian Provincial Key Laboratory of Innovative Drug Target Research, State Key Laboratory of Vaccines for Infectious Diseases, Xiang An Biomedicine Laboratory, MOE Key Laboratory of Spectrochemical Analysis and Instrumentation, School of Pharmaceutical Sciences, Xiamen University, Xiamen, Fujian 361102, China.
Juncheng WanFujian Provincial Key Laboratory of Innovative Drug Target Research, State Key Laboratory of Vaccines for Infectious Diseases, Xiang An Biomedicine Laboratory, MOE Key Laboratory of Spectrochemical Analysis and Instrumentation, School of Pharmaceutical Sciences, Xiamen University, Xiamen, Fujian 361102, China.
Qing YangFujian Provincial Key Laboratory of Innovative Drug Target Research, State Key Laboratory of Vaccines for Infectious Diseases, Xiang An Biomedicine Laboratory, MOE Key Laboratory of Spectrochemical Analysis and Instrumentation, School of Pharmaceutical Sciences, Xiamen University, Xiamen, Fujian 361102, China.
Rong DingFujian Provincial Key Laboratory of Innovative Drug Target Research, State Key Laboratory of Vaccines for Infectious Diseases, Xiang An Biomedicine Laboratory, MOE Key Laboratory of Spectrochemical Analysis and Instrumentation, School of Pharmaceutical Sciences, Xiamen University, Xiamen, Fujian 361102, China.
Xiang GaoFujian Provincial Key Laboratory of Innovative Drug Target Research, State Key Laboratory of Vaccines for Infectious Diseases, Xiang An Biomedicine Laboratory, MOE Key Laboratory of Spectrochemical Analysis and Instrumentation, School of Pharmaceutical Sciences, Xiamen University, Xiamen, Fujian 361102, China.ORCID https://orcid.org/0000-0002-3774-1852
Zhiping ZengFujian Provincial Key Laboratory of Innovative Drug Target Research, State Key Laboratory of Vaccines for Infectious Diseases, Xiang An Biomedicine Laboratory, MOE Key Laboratory of Spectrochemical Analysis and Instrumentation, School of Pharmaceutical Sciences, Xiamen University, Xiamen, Fujian 361102, China.
Changliang RenFujian Provincial Key Laboratory of Innovative Drug Target Research, State Key Laboratory of Vaccines for Infectious Diseases, Xiang An Biomedicine Laboratory, MOE Key Laboratory of Spectrochemical Analysis and Instrumentation, School of Pharmaceutical Sciences, Xiamen University, Xiamen, Fujian 361102, China.ORCID https://orcid.org/0000-0003-2657-9412

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Peptide transporters are integral membrane proteins responsible for the cellular uptake of dipeptides and tripeptides from the extracellular environment, which play pivotal roles in nutrient absorption, antigen presentation, and cellular signaling. Despite their essential biological functions, the development of artificial peptide transporters capable of efficiently transporting charge-neutral peptides, which are highly polar and prone to aggregation, remains a significant challenge. Herein, we introduce a novel class of peptide transporters involving the integration of anion and cation transport functionalities. Notably,

Indexed as

artificial peptide transporterscancer therapyH-bondssupramolecular chemistrytransmembrane transport

Identifiers

PMID40575313
PMCPMC12188416

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.