ArticleCureus2025
Preoperative Epidural Steroid Injections and Surgical Site Infection Risk in Lumbar Spine Surgery: A Retrospective Cohort Study.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Modulation of Surgical Site Infection Risk in Spinal and Thoracic Surgeries Through Operative Parameters: A Narrative Review.Journal of clinical medicine · 2025Review
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLow back pain is a leading cause of work-related disability worldwide. Epidural steroid injections (ESIs) are commonly used as nonoperative treatments for patients with degenerative lumbar spine pathology. It is imperative to further elucidate the association between preoperative ESIs and postoperative outcomes in this population. This study seeks to evaluate the association between the timing of preoperative ESIs and the incidence of surgical site infections (SSIs) in patients undergoing lumbar spine surgery.
methodsThis retrospective study analyzed patients who underwent lumbar spine surgery from January 2020 to December 2021. Patients were stratified based on ESI status: no ESI, most recent ESI within three months preoperatively (early group), and most recent ESI equal to or greater than three months preoperatively (late group). All patients were followed for at least one year postoperatively to monitor for SSI. Bivariate correlation analysis using Spearman's rank correlation coefficient was performed to identify risk factors for SSI. Infection rates across ESI groups were compared using Pearson's chi-square test, Fisher's exact test, or the chi-square test of independence, selected based on sample size and expected cell counts.
resultsAmong 94 patients, 49 received a preoperative ESI. Of these, 11 patients were in the early ESI group and 38 in the late ESI group. The overall infection rate was 2.2%, with one infection in each ESI subgroup. No significant difference in SSI rates was observed between the early and late ESI groups (p=0.171). Higher BMI, use of Disease-Modifying Antirheumatic Drugs (DMARDs), and higher American Society of Anesthesiologists (ASA) scores were associated with an increased SSI risk (p<0.05).
conclusionsThe timing of preoperative ESI does not significantly influence SSI risk in lumbar spine surgery. This study also highlights the role of elevated BMI, DMARD use, and ASA scores as potential risk factors for SSI in patients receiving preoperative ESI. Mitigating infection risk should focus on addressing modifiable factors such as BMI, DMARD use, and ASA scores rather than ESI timing.
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