ArticleCureus2025
Corticosteroid-Refractory Bullous Pemphigoid Due to Immune Checkpoint Inhibitors: A Telemedicine Challenge.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed, 1 synthesis or guideline pooled it.
- Immune checkpoint inhibitor-induced bullous pemphigoid: a systematic review of clinical characteristics and outcomes based on case reports.Frontiers in immunology · 2026Pooled it
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Immune checkpoint inhibitors (ICIs) have become the new standard of care for many malignancies due to their higher efficacy and safer toxicity profile. However, immune-related adverse events (irAEs) can occur unpredictably and in a wide range of organs. Most irAEs present with mild to moderate toxicities. Rarely, severe and life-threatening events occur and can be fatal. Therefore, immediate recognition and management of irAEs are important. Early diagnosis and initiation of treatment with corticosteroids, coupled with diligent follow-up by specialists, are critical steps in optimizing outcomes for patients experiencing irAEs. We present a case report that illustrates the development and progression of severe cutaneous toxicity presenting as a rare bullous pemphigoid rash at the end of two years on nivolumab. It is essential to note that this occurred in an outpatient setting during the COVID-19 pandemic. In coordination with rural providers and telemedicine, the patient's corticosteroid-refractory ICI toxicity was treated successfully.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.