ArticleCureus2025
Association Between a Decrease in Blood Monocyte Counts and Necrotizing Enterocolitis in Preterm Infants.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- The role of myeloid cells in the pathogenesis of necrotizing enterocolitis; a scoping review.Frontiers in pediatrics · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo explore the association between absolute monocyte count (AMC) and necrotizing enterocolitis (NEC) in preterm neonates and to assess whether a fall in AMC can be used as a biomarker to predict an increased risk for NEC. STUDY
designThis was a retrospective study of preterm neonates with NEC or a first episode of feeding intolerance (FI). Their complete blood count (CBC) was evaluated for AMC at three time points, first at baseline, second at the onset of NEC/FI, and third afterwards. Statistical analysis was done using Student's t-test and the chi-squared test. The p-value of <0.05 was considered significant.
resultsOf the total 92 newborns, 29 (31.5%) had NEC, while 63 (68.5%) had FI. NEC and FI groups were comparable in gestational age (GA) and birth weight. There was a significant increase in AMC in the FI group (p<0.001) from baseline to the onset of FI. However, the AMC had a fall in the NEC group from baseline to the onset of NEC, which was not statistically significant (p=0.074).
conclusionA decrease in AMC was associated with the presence of NEC. A fall in the AMC could be a biomarker to identify an increased risk of NEC in preterm neonates with feeding problems.
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