ArticleCureus2025
Synchronous Sigmoid Colon and Small Bowel Adenocarcinomas: A Rare Case of Dual Primary Malignancies Presenting With Acute Bowel Obstruction.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Synchronous colorectal and small bowel adenocarcinomas are exceptionally rare. This case report presents a 65-year-old male patient with acute bowel obstruction who underwent an emergency laparotomy. Intraoperative findings revealed synchronous sigmoid colon and small bowel tumors with peritoneal metastases. The patient underwent sigmoidectomy, small bowel resection, and metastasectomy. Histopathology confirmed two distinct primary adenocarcinomas. Postoperative management included KRAS mutation-guided chemotherapy. At the two-year follow-up, the patient remained disease-free. This case highlights the importance of thorough intraoperative exploration in emergency presentations and demonstrates the potential for favorable outcomes with aggressive multimodal treatment in synchronous gastrointestinal malignancies.
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